Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 16/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051369 | 0.94 | NR1H2 (0.39) | NR1H2NR1H3 | |
| SCHEMBL3044637 | 0.91 | NR1H2 (0.39) | NR1H2NR1H3TBK1 | |
| SCHEMBL3051382 | 0.90 | NR1H2 (0.36) | NR1H2NR1H3TBK1 | |
| SCHEMBL3034089 | 0.90 | NR1H2 (0.35) | NR1H2NR1H3TBK1 | |
| SCHEMBL3037479 | 0.90 | NR1H2 (0.35) | NR1H2NR1H3TBK1 | |
| SCHEMBL3051443 | 0.89 | TBK1 (0.36) | NR1H2NR1H3TBK1 | |
| SCHEMBL3044249 | 0.89 | NR1H2 (0.35) | NR1H2NR1H3TBK1 | |
| SCHEMBL3840174 | 0.89 | NR1H2 (0.37) | NR1H2NR1H3TBK1 | |
| SCHEMBL3037182 | 0.88 | ACHE (0.37) | NR1H2TBK1 | |
| SCHEMBL3033517 | 0.87 | EED (0.34) | NR1H2NR1H3TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |