Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826549 | 0.85 | SERPINE1 (0.44) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL29083879 | 0.84 | TDP1 (0.52) | CYP3A4TDP1MAPTNPC1RAB9A | |
| SCHEMBL5049251 | 0.81 | SERPINE1 (0.50) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL29083828 | 0.81 | KMT2A (0.49) | CYP3A4TDP1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL5053888 | 0.81 | RAB9A (0.44) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2615416 | 0.78 | ABCB11 (0.62) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL5050530 | 0.77 | CES2 (0.41) | CYP3A4TDP1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL3625514 | 0.77 | ESR1 (0.44) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL823817 | 0.77 | ESR1 (0.44) | ABCB11CYP3A4ADRA2BOPRD1SCN5A | |
| SCHEMBL825582 | 0.77 | ESR1 (0.44) | ABCB11CYP3A4ADRA2BOPRD1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798250-B1 | Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules | IMEC INTER UNI MICRO ELECTR (BE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1798250-A2 | Molecules suitable for binding to a metal layer for covalently immobilizing biomolecules | INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM vzw (IMEC) (BE) | 2007-06-20 | — | — | EP | disclosed |