Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967835 | 0.79 | NPSR1 (0.53) | KDM4EALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL3386303 | 0.75 | F12 (0.54) | ALDH1A1HPGDSMN1; SMN2GAARAB9A | |
| Bromide SCHEMBL964193 | 0.74 | F12 (0.53) | ALDH1A1HPGDSMN1; SMN2GAARAB9A | |
| SCHEMBL5044103 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HPGDNPSR1SMN1; SMN2RAB9A | |
| Bromide SCHEMBL965108 | 0.71 | ALDH1A1 (0.37) | ALDH1A1HPGDNPSR1SMN1; SMN2RAB9A | |
| SCHEMBL961855 | 0.71 | KDM4E (0.59) | KDM4EALDH1A1HPGDNPSR1SMN1; SMN2 | |
| SCHEMBL961718 | 0.70 | NPSR1 (0.42) | ALDH1A1HPGDNPSR1SMN1; SMN2GAA | |
| Bromide SCHEMBL964455 | 0.67 | F12 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL8660399 | 0.66 | KCNQ3 (0.42) | ALDH1A1SMN1; SMN2GAARAB9AMAPT | |
| SCHEMBL9471605 | 0.65 | KCNQ3 (0.41) | ALDH1A1SMN1; SMN2GAARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024349-B1 | COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | ABBVIE INC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-20080064699-A1 | Such as N-[3-(2-methoxyethyl)-1,3-thiazol-2(3H)-ylidene]adamantane-1-carboxamide; neuropathic, nociceptive and/or inflammatory pain; neuroprotection | ABBVIE INC. | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064699-A1 | Such as N-[3-(2-methoxyethyl)-1,3-thiazol-2(3H)-ylidene]adamantane-1-carboxamide; neuropathic, nociceptive and/or inflammatory pain; neuroprotection | OPRL1, OPRK1, OPRD1 | KDM4E 3198/4885ALDH1A1 81/4885HPGD 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.