Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | CASP7 | P55210 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | FTO | Q9C0B1 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | ABCC4 | O15439 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diacerein SCHEMBL29944894 | 1.00 | TTR (1.00) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL25784 | 1.00 | TTR (1.00) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL29423907 | 1.00 | TTR (1.00) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL7438555 | 0.99 | TTR (0.97) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL5078956 | 0.99 | TTR (0.97) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL787907 | 0.99 | TTR (0.97) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL2326532 | 0.93 | TTR (0.86) | TTRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL23655432 | 0.92 | TTR (0.84) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL5712120 | 0.92 | MEN1 (0.84) | TTRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL16549421 | 0.90 | TTR (0.82) | TTRALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151309-A1 | METHODS FOR REGULATING INDUCED PLURIPOTENT STEM CELL GENERATION AND COMPOSITIONS THEREOF | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2012-11-08 | — | — | WO | disclosed |
| EP-1931760-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | The University of Alabama (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007044693-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | THE UNIVERSITY OF ALABAMA (US) | 2007-04-19 | — | — | WO | disclosed |