Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 9/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.97 |
| ▸ | HPGD | P15428 | 3/20 | 0.97 |
| ▸ | MEN1 | O00255 | 2/20 | 0.97 |
| ▸ | LMNA | P02545 | 2/20 | 0.97 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.97 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.97 |
| ▸ | CASP7 | P55210 | 2/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.97 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.97 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.97 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.97 |
| ▸ | USP2 | O75604 | 1/20 | 0.97 |
| ▸ | TP53 | P04637 | 1/20 | 0.97 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.97 |
| ▸ | HTR1A | P08908 | 1/20 | 0.97 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diacerein SCHEMBL5051685 | 0.99 | TTR (1.00) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL25784 | 0.99 | TTR (1.00) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL29423907 | 0.99 | TTR (1.00) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL29944894 | 0.99 | TTR (1.00) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL7438555 | 0.97 | TTR (0.97) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL787907 | 0.97 | TTR (0.97) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL2326532 | 0.92 | TTR (0.86) | TTRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL23655432 | 0.91 | TTR (0.84) | TTRALDH1A1KDM4EHPGDMEN1 | |
| Diacerein SCHEMBL5712120 | 0.91 | MEN1 (0.84) | TTRALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL16549421 | 0.89 | TTR (0.82) | TTRALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521205-B | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2023-11-10 | — | — | CN | claimed |
| CN-115521205-A | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2022-12-27 | — | — | CN | claimed |
| WO-1998056750-A1 | A PROCESS FOR THE PREPARATION OF DIACEREIN | SYNTECO S.R.L. (IT) | 1998-12-17 | — | — | WO | claimed |
| CN-115521205-B | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115521205-B | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115521205-B | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115521205-A | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-115521205-A | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-115521205-A | Crystal form of diacerein sodium salt and preparation method thereof | 北京百奥药业有限责任公司 | 2022-12-27 | — | — | CN | disclosed |
| EP-2497761-A1 | Process for the purification of anthraquinone derivatives | ICROM S.p.A. (IT) | 2012-09-12 | — | — | EP | disclosed |
| EP-1296928-B1 | A PROCESS FOR THE PURIFICATION OF DIACEREIN | SYNTECO SPA (IT) | 2008-11-19 | — | — | EP | disclosed |
| EP-1669344-A1 | METHOD FOR THE PURIFICATION OF CRUDE DIACEREIN BY MEANS OF TOLUENE | Interquim, S.A. De C.V. (MX) | 2006-06-14 | — | — | EP | disclosed |
| CN-1187311-C | process for purifying diacerein | SYNTECO SPA (IT) | 2005-02-02 | — | — | CN | disclosed |
| EP-1177164-B1 | A PROCESS FOR THE PURIFICATION OF DIACEREIN | SYNTECO SPA (IT) | 2004-09-29 | — | — | EP | disclosed |
| EP-1296928-A1 | A PROCESS FOR THE PURIFICATION OF DIACEREIN | Synteco S.p.A. (IT) | 2003-04-02 | — | — | EP | disclosed |
| CN-1349495-A | Process for the purification of diacerein | SYNTECO SPA (IT) | 2002-05-15 | — | — | CN | disclosed |
| EP-1177164-A1 | A PROCESS FOR THE PURIFICATION OF DIACEREIN | Synteco S.p.A. (IT) | 2002-02-06 | — | — | EP | disclosed |
| WO-2001096276-A1 | A PROCESS FOR THE PURIFICATION OF DIACEREIN | SYNTECO S.P.A. (IT) | 2001-12-20 | — | — | WO | disclosed |
| WO-2000068179-A1 | A PROCESS FOR THE PURIFICATION OF DIACEREIN | SYNTECO S.P.A. (IT) | 2000-11-16 | — | — | WO | disclosed |
| WO-1998056750-A1 | A PROCESS FOR THE PREPARATION OF DIACEREIN | SYNTECO S.R.L. (IT) | 1998-12-17 | — | — | WO | disclosed |