Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 11/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.57 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.57 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.57 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.57 |
| ▸ | RAF1 | P04049 | 3/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942701 | 0.89 | TEK (0.70) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29363034 | 0.89 | TEK (0.70) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| Imidazole SCHEMBL7109750 | 0.83 | TEK (0.55) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL30290596 | 0.78 | MAPK13 (0.62) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3454813 | 0.77 | MAPK14 (0.71) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL3194058 | 0.75 | TEK (0.73) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| Imidazole SCHEMBL26632663 | 0.75 | MAPK13 (0.76) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL11212515 | 0.75 | MAPK13 (0.76) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7795648 | 0.74 | MAPK14 (0.67) | TEKMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29464077 | 0.74 | MAPK14 (0.69) | TEKMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381516-B2 | Multiphoton photosensitization system | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-03 | — | — | US | disclosed |
| US-20040067431-A1 | Multiphoton photosensitization system | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-08 | — | — | US | disclosed |