⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800756 | 0.86 | ALDH1A1 (0.35) | — | |
| SCHEMBL1352707 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL28573457 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL2418354 | 0.78 | ALDH1A1 (0.38) | — | |
| SCHEMBL15694681 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL1351936 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL4318074 | 0.75 | ALDH1A1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL5350159 | 0.75 | DNM1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL5352701 | 0.75 | DNM1 (0.40) | — | |
| SCHEMBL13434821 | 0.73 | FDPS (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7862807-B2 | Dendrimers as molecular translocators | UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2011-01-04 | — | — | US | disclosed |
| US-20080221020-A1 | Dendrimers as Molecular Translocators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-11 | — | — | US | disclosed |
| US-20060216265-A1 | Dendrimers as molecular translocators | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-09-28 | — | — | US | disclosed |
| WO-2004009666-A2 | DENDRIMERS AS MOLECULAR TRANSLOCATORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-01-29 | — | — | WO | disclosed |