SCHEMBL5052168

SCHEMBL5052168

CCO[Si](CCCNC(=O)c1ccccc1O)(OCC)OCC

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ NAAA Q02083 1/20 0.63
▸ HPGD P15428 4/20 0.56
▸ HTT P42858 3/20 0.56
▸ TSHR P16473 2/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ NPC1 O15118 1/20 0.56
▸ MAPT P10636 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ NLRP1 Q9C000 1/20 0.56
▸ HCRTR1 O43613 2/20 0.52
▸ MEN1 O00255 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ KMT2A Q03164 1/20 0.50
▸ ALOX5 P09917 1/20 0.50
▸ NAMPT P43490 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.47
▸ ESRRG P62508 1/20 0.47
▸ HDAC7 Q8WUI4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14264611 0.86 HPGD (0.58) HPGDHTTTSHRNPC1HCRTR1
SCHEMBL1221419 0.86 HTT (0.56) NAAAHPGDHTTTSHRMAPT
SCHEMBL23302178 0.85 HTT (0.55) NAAAHPGDHTTTSHRHSD17B10
SCHEMBL29394858 0.85 HTT (0.55) NAAAHPGDHTTTSHRHSD17B10
SCHEMBL9494657 0.85 HPGD (0.56) NAAAHPGDHTTTSHRALDH1A1
Malonic Acid SCHEMBL27542061 0.83 HTT (0.52) NAAAHPGDHTTTSHRALDH1A1
SCHEMBL16804323 0.82 HCRTR1 (0.51) NAAAHPGDHTTTSHRALDH1A1
SCHEMBL29127798 0.81 NAAA (0.60) NAAAHPGDALDH1A1NPC1POLB
SCHEMBL13700186 0.81 NAAA (0.68) NAAAHPGDHTTTSHRALDH1A1
SCHEMBL3148607 0.81 NAAA (0.88) NAAAHPGDHTTTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12343424-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-07-01 — — US disclosed
US-20220339091-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2022-10-27 — — US disclosed
US-11389386-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2022-07-19 — — US disclosed
US-20190038537-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2019-02-07 — — US disclosed
WO-2017132655-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-08-03 — — WO disclosed
US-20080063720-A1 Cadmium telluride, cadmium selenide nanoparticles; water, lipid soluble; conjugated to drugs and theraputics to target tissues, membranes, cells, tumors, parasites, pathogens; diagnostics PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN, THE (IE) 2008-03-13 — — US disclosed
WO-2005105035-A2 TARGETED NANOPARTICLES FOR DRUG DELIVERY THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH (IE) 2005-11-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12343424-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens SQLE, STS, DSG1 NAAA 3075/4885HPGD 582/4885HTT 2647/4885
US-11389386-B2 Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens SQLE, STS, RAD52 NAAA 3195/4885HPGD 648/4885HTT 2661/4885
US-20190038537-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS SQLE, STS, RAD52 NAAA 3438/4885HPGD 673/4885HTT 2910/4885
US-20220339091-A1 PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS SQLE, STS, DSG1 NAAA 3075/4885HPGD 582/4885HTT 2647/4885
US-20080063720-A1 Cadmium telluride, cadmium selenide nanoparticles; water, lipid soluble; conjugated to drugs and theraputics to target tissues, membranes, cells, tumors, parasites, pathogens; diagnostics CD2BP2, TBCD, SLC30A6 NAAA 1970/4885HPGD 3140/4885HTT 3783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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