SCHEMBL50528

SCHEMBL50528

CC(=O)NCCCCCO

nearest known ligand 0.80

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.80
MAPK1 P28482 1/20 0.80
HIF1A Q16665 1/20 0.80
PAOX Q6QHF9 3/20 0.64
ADRA1A P35348 1/20 0.61
TDP1 Q9NUW8 1/20 0.53
NAAA Q02083 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
TSHR P16473 1/20 0.46
ACHE P22303 6/20 0.46
EPHX1 P07099 2/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1499636 1.00 KDM4E (0.80) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1036792 1.00 KDM4E (0.80) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL27052549 1.00 KDM4E (0.80) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL48871 0.97
SCHEMBL48733 0.90
SCHEMBL14739904 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14740132 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL6516953 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1900654 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1847535 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-12-07 US claimed
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2019-04-11 US claimed
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-29 US claimed
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2015-09-17 US claimed
US-9060518-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-06-23 US claimed
JP-2011509971-A 2011-03-31 JP claimed
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2011-03-03 US claimed
EP-2234489-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE Bayer CropScience AG (DE) 2010-10-06 EP claimed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO claimed
EP-4727916-A1 MIXED AMIDE ESTER CONTAINING LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2026-04-22 EP disclosed
US-20250333559-A1 INTRINSICALLY REPROCESSABLE DOUBLE-NETWORK ELASTOMERS UNIV VIRGINIA PATENT FOUNDATION (US) 2025-10-30 US disclosed
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF Sea Pharmaceuticals LLC. (US) 2025-03-06 US disclosed
US-20250025427-A1 MIXED AMIDE ESTER CONTAINING LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2025-01-23 US disclosed
WO-2024259356-A1 MIXED AMIDE ESTER CONTAINING LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2024-12-19 WO disclosed
EP-0408634-A1 ORGANIC SYNTHESIS EMPLOYING SUPERCRITICAL CARBON DIOXIDE AS A REACTION SOLVENT PROTEIN TECHNOLOGIES, INC. (US) 1991-01-23 EP disclosed
EP-0271656-B1 REACTIVE AMINO ALKOXY-TRIPHENE DIOXAZINE DYES BAYER AG (DE) 1990-08-01 EP disclosed
US-4874857-A FIBER-REACTIVE DYES BAYER AKTIENGESELLSCHAFT (DE) 1989-10-17 US disclosed
WO-1989008659-A1 ORGANIC SYNTHESIS EMPLOYING SUPERCRITICAL CARBON DIOXIDE AS A REACTION SOLVENT PROTEIN TECHNOLOGIES, INC. (US) 1989-09-21 WO disclosed
EP-0299328-A2 Reactive dyes BAYER AG (DE) 1989-01-18 EP disclosed
EP-0271656-A1 Reactive amino alkoxy-triphene dioxazine dyes BAYER AG (DE) 1988-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074887-A1 PHARMACEUTICAL COMPOSITIONS OF 6-(2-(2H-TETRAZOL-5-YL)ETHYL)DECAHYDROISOQUINOLINE-3-CARBOXYLIC ACID AND DERIVATIVES THEREOF GABRQ, GRIK5, CYP3A7 KDM4E 852/4885MAPK1 4101/4885HIF1A 2913/4885
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-20250025427-A1 MIXED AMIDE ESTER CONTAINING LIPIDS FOR USE IN LIPID NANOPARTICLES LIPA, LIPC, PHOSPHO1 KDM4E 4092/4885MAPK1 2260/4885HIF1A 2170/4885
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.