SCHEMBL5052807

SCHEMBL5052807

OCC(O)C1OCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6543860 1.00
SCHEMBL6715406 0.79 THRB (0.39)
SCHEMBL4017324 0.77
SCHEMBL5071013 0.75
SCHEMBL13418946 0.74
SCHEMBL15013124 0.74 LMNA (0.35)
SCHEMBL8837758 0.73
SCHEMBL14515471 0.71
SCHEMBL2329761 0.71
SCHEMBL3517410 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2928503-A1 AURISTATIN COMPOUNDS AND CONJUGATES THEREOF Mersana Therapeutics, Inc. (US) 2015-10-14 EP disclosed
WO-2014093379-A1 AURISTATIN COMPOUNDS AND CONJUGATES THEREOF MERSANA THERAPEUTICS, INC. (US) 2014-06-19 WO disclosed
WO-2008048695-A2 SYNTHESIS AND APPLICATIONS OF NANOMATERIALS DERIVED FROM SELF-ASSEMBLED DIACETYLENIC TRIGLYCERIDES KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) 2008-04-24 WO disclosed
EP-1175382-B1 METHOD FOR THE DIHYDROXYLATION OF OLEFINS USING TRANSITION-METAL CATALYSTS BAYER CHEMICALS AG (DE) 2005-02-09 EP disclosed
US-6825377-B1 CATALYTIC OXIDATION USING OXYGEN OR GAS MIXTURE IN PRESENCE OF OSMIUM, RUTHENIUM, OR MANGANESE COMPOUND IN WATER; ADDING AMINE FOR CATALYST SELECTIVITY BAYER AKTIENGESELLSCHAFT (DE) 2004-11-30 US disclosed
EP-1175379-B1 METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS BAYER CHEMICALS AG (DE) 2004-01-02 EP disclosed
US-6472570-B1 Method for the asymmetric dihydroxylation of olefins, using osmium catalysts BAYER AKTIENGESELLSCHAFT (DE) 2002-10-29 US disclosed
EP-1175382-A1 METHOD FOR THE DIHYDROXYLATION OF OLEFINS USING TRANSITION-METAL CATALYSTS Bayer Aktiengesellschaft (DE) 2002-01-30 EP disclosed
EP-1175379-A1 METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS Bayer Aktiengesellschaft (DE) 2002-01-30 EP disclosed
WO-2000064848-A1 METHOD FOR THE DIHYDROXYLATION OF OLEFINS USING TRANSITION-METAL CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed
WO-2000064844-A1 METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed
US-4755323-A Mixture of liquid crystalline compounds including substituted para-dioxane MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-07-05 US disclosed