Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543860 | 0.79 | — | — | |
| SCHEMBL5052807 | 0.79 | — | — | |
| SCHEMBL5071013 | 0.76 | — | — | |
| SCHEMBL11681754 | 0.70 | — | — | |
| SCHEMBL2207927 | 0.69 | THRB (0.71) | THRBALDH1A1LMNA | |
| SCHEMBL10581335 | 0.69 | THRB (0.71) | THRBALDH1A1LMNA | |
| SCHEMBL9742446 | 0.69 | THRB (0.71) | THRBALDH1A1LMNA | |
| SCHEMBL7157355 | 0.69 | THRB (0.71) | THRBALDH1A1LMNA | |
| SCHEMBL6578925 | 0.67 | LMNA (0.40) | THRBALDH1A1LMNA | |
| SCHEMBL6217339 | 0.67 | LMNA (0.40) | THRBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033462-A2 | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO [2, 3-b] FURAN AND RELATED COMPOUNDS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2004-04-22 | — | — | WO | disclosed |