Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830454 | 0.87 | TK1 (0.43) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL4542149 | 0.87 | TK1 (0.43) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL20526458 | 0.85 | PYGM (0.46) | PYGMTK1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL28040328 | 0.83 | PYGM (0.45) | PYGMTK1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL28749266 | 0.82 | PYGM (0.44) | PYGMTK1SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL27703606 | 0.79 | SLC28A1 (0.44) | — | |
| SCHEMBL65485 | 0.79 | SLC28A1 (0.44) | — | |
| SCHEMBL5614068 | 0.74 | PYGM (0.50) | PYGMTK1SMN1; SMN2LMNAALOX12 | |
| SCHEMBL9393373 | 0.73 | SLC28A1 (0.39) | — | |
| SCHEMBL29364921 | 0.72 | TK1 (0.45) | TK1LMNATSHRBLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080026992-A1 | Tyrosine Phosphorylation of Cdk Inhibitor Proteins of the Cip/Kip Family | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2008-01-31 | — | — | US | disclosed |
| EP-1687331-A1 | TYROSINE PHOSPHORYLATION OF CDK INHIBITOR PROTEINS OF THE CIP/KIP FAMILY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005040207-A1 | TYROSINE PHOSPHORYLATION OF CDK INHIBITOR PROTEINS OF THE CIP/KIP FAMILY | F. HOFFMANN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | disclosed |