Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.45 |
| ▸ | TK1 | P04183 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694341 | 0.86 | TK1 (0.43) | TK1 | |
| SCHEMBL5052901 | 0.83 | PYGM (0.46) | PYGMTK1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL20526458 | 0.83 | PYGM (0.46) | PYGMTK1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL28749266 | 0.81 | PYGM (0.44) | PYGMTK1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL6536213 | 0.78 | TK1 (0.42) | TK1LMNABLMNPSR1ADRA1A | |
| SCHEMBL28239487 | 0.77 | TK1 (0.41) | TK1LMNABLMADRA1A | |
| SCHEMBL11309914 | 0.77 | LMNA (0.47) | TK1LMNASMN1; SMN2TSHRPMP22 | |
| SCHEMBL27651863 | 0.77 | TK1 (0.41) | TK1TK2 | |
| SCHEMBL28293851 | 0.77 | TK1 (0.39) | TK1NPSR1 | |
| SCHEMBL17224727 | 0.76 | TK1 (0.39) | TK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105056226-A | Compositions and methods for the treatment of infections and tumors | UNIV EMORY | 2015-11-18 | — | — | CN | disclosed |