Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047930 | 0.89 | MEN1 (0.52) | MEN1KMT2ANR1H2NR1H3LMNA | |
| SCHEMBL5053629 | 0.75 | CYP1A2 (0.47) | MEN1KMT2ANR1H2NR1H3LMNA | |
| SCHEMBL29009119 | 0.74 | CYP19A1 (0.47) | MEN1KMT2ANR1H2NR1H3LMNA | |
| SCHEMBL5051897 | 0.74 | CDC7 (0.60) | MEN1KMT2ANR1H2NR1H3LMNA | |
| SCHEMBL5049567 | 0.74 | CDC7 (0.60) | MEN1KMT2ANR1H2NR1H3LMNA | |
| SCHEMBL5049603 | 0.74 | MEN1 (0.46) | MEN1KMT2ANR1H2NR1H3LMNA | |
| SCHEMBL3599212 | 0.73 | CYP1A2 (0.54) | MEN1KMT2ALMNAL3MBTL1KDM4E | |
| SCHEMBL3605027 | 0.72 | SLC2A2 (0.58) | MEN1KMT2AKDM4EGAANPSR1 | |
| SCHEMBL9304768 | 0.71 | CYP19A1 (0.58) | MEN1KMT2ANR1H3LMNAL3MBTL1 | |
| SCHEMBL30928890 | 0.71 | ALDH1A1 (0.65) | MEN1KMT2ANR1H2NR1H3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | claimed |
| EP-1921072-A1 | 1,2,3-Triazole derivatives as cannabinoid-receptor modulators | Laboratorios del Dr. Esteve S.A. (ES) | 2008-05-14 | — | — | EP | disclosed |