Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.38 |
| ▸ | BHMT | Q93088 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526326 | 1.00 | PDCD1LG2 (0.48) | PDCD1LG2CD274MMEDPP4DPP8 | |
| SCHEMBL8526147 | 1.00 | PDCD1LG2 (0.48) | PDCD1LG2CD274MMEDPP4DPP8 | |
| SCHEMBL30462197 | 0.94 | PDCD1LG2 (0.44) | PDCD1LG2CD274MMEDPP4DPP8 | |
| SCHEMBL29599569 | 0.89 | ENPEP (0.50) | ENPEP | |
| SCHEMBL29867109 | 0.89 | PDCD1LG2 (0.50) | PDCD1LG2CD274MMEVSIR | |
| SCHEMBL31319509 | 0.88 | OPRM1 (0.46) | PDCD1LG2CD274MME | |
| SCHEMBL8528144 | 0.88 | CD274 (0.57) | PDCD1LG2CD274MMEDPP4DPP8 | |
| SCHEMBL29572257 | 0.88 | CD274 (0.57) | PDCD1LG2CD274MMEDPP4DPP8 | |
| SCHEMBL29572216 | 0.88 | CD274 (0.57) | PDCD1LG2CD274MMEDPP4DPP8 | |
| SCHEMBL5998197 | 0.88 | CD274 (0.57) | PDCD1LG2CD274MMEDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319032-B2 | Non-sugar sweeteners for use in test devices | MEDTOX (US) | 2008-01-15 | — | — | US | disclosed |
| US-20050239214-A1 | Non-sugar sweeteners for use in test devices | MEDTOX SCIENTIFIC, INC. (US) | 2005-10-27 | — | — | US | disclosed |
| EP-0768041-B1 | Sweetener salts | HOLLAND SWEETENER CO (NL) | 2002-12-18 | — | — | EP | disclosed |
| EP-0691346-B1 | Novel aspartyldipeptide derivatives and sweetener | AJINOMOTO KK (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5856579-A | Adduct salts of novel substituted benzylamines and a process for optically resolving them | AJINOMOTO CO., INC. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5827562-A | REACTION PRODUCT OF ASPARTIC ACID AND INTENSE SWEETENER NOT DERIVED FROM ASPARTIC ACID | HOLLAND SWEETENER COMPANY V.O.F. (NL) | 1998-10-27 | — | — | US | disclosed |
| US-5723165-A | ARTIFICIAL SWEETENERS | AJINOMOTO CO., INC. (JP) | 1998-03-03 | — | — | US | disclosed |
| CN-1155535-A | Adduct salts of novel substituted benzyl amines and process for optically resolving them | AJINOMOTO KK (JP) | 1997-07-30 | — | — | CN | disclosed |
| EP-0768041-A1 | Sweetener salts | Holland Sweetener Company V.o.F. (NL) | 1997-04-16 | — | — | EP | disclosed |
| EP-0691346-A1 | Novel aspartyldipeptide derivatives and sweetener | Ajinomoto Co., Inc. (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-4517379-A | ARTIFICIAL SWEETENER | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0069811-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-10-24 | — | — | EP | disclosed |
| US-4454328-A | SWEETENERS | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4399163-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0069811-A1 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1983-01-19 | — | — | EP | disclosed |