SCHEMBL8526326

SCHEMBL8526326

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nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDCD1LG2 Q9BQ51 2/20 0.48
CD274 Q9NZQ7 2/20 0.48
MME P08473 2/20 0.42
DPP4 P27487 1/20 0.39
DPP8 Q6V1X1 1/20 0.39
DPP9 Q86TI2 1/20 0.39
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
VSIR Q9H7M9 2/20 0.38
BHMT Q93088 1/20 0.37
ENPEP Q07075 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5053902 1.00 PDCD1LG2 (0.48) PDCD1LG2CD274MMEDPP4DPP8
SCHEMBL8526147 1.00 PDCD1LG2 (0.48) PDCD1LG2CD274MMEDPP4DPP8
SCHEMBL30462197 0.94 PDCD1LG2 (0.44) PDCD1LG2CD274MMEDPP4DPP8
SCHEMBL29599569 0.89 ENPEP (0.50) ENPEP
SCHEMBL29867109 0.89 PDCD1LG2 (0.50) PDCD1LG2CD274MMEVSIR
SCHEMBL31319509 0.88 OPRM1 (0.46) PDCD1LG2CD274MME
SCHEMBL8528144 0.88 CD274 (0.57) PDCD1LG2CD274MMEDPP4DPP8
SCHEMBL29572257 0.88 CD274 (0.57) PDCD1LG2CD274MMEDPP4DPP8
SCHEMBL29572216 0.88 CD274 (0.57) PDCD1LG2CD274MMEDPP4DPP8
SCHEMBL5998197 0.88 CD274 (0.57) PDCD1LG2CD274MMEDPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743479-A1 ADENOVIRUSES Theolytics Ltd. (GB) 2026-05-20 EP claimed
EP-4743101-A1 MUTATED ADENOVIRUSES WITH IMPROVED REPLICATION AND THEIR USE FOR TREATING CANCER Theolytics Ltd. (GB) 2026-05-20 EP claimed
WO-2025012636-A1 MUTATED ADENOVIRUSES WITH IMPROVED REPLICATION AND THEIR USE FOR TREATING CANCER THEOLYTICS LTD (GB) 2025-01-16 WO claimed
WO-2025012637-A1 ADENOVIRUSES THEOLYTICS LTD (GB) 2025-01-16 WO claimed
WO-2025002589-A1 TISSUE EXTRACELLULAR PEPTIDE PATTERNS DEDICATED FOR GENERATION OF ANTI-CANCER VACCINES AGAINST SALIVARY GLAND TUMOR, IDENTIFICATION AND ISOLATION OF SALIVARY GLAND TUMOR SPECIFIC T CELLS IN HUMANS Uniwersytet Gdański (PL) 2025-01-02 WO claimed
US-20240391958-A1 KEANUMYCINS AND USES THEREOF IN MEDICINE AND PLANT PROTECTION LEIBNIZ-INSTITUT FÜR NATURSTOFF-FORSCHUNG UND INFEKTIONSBIOLOGIE E. V. HANS-KNÖLL-INSTITUT (HKI) (DE) 2024-11-28 US claimed
CN-115047120-A Dansyl chloride derivatization method for analyzing and detecting dipeptide substances in white spirit Daqu 贵州茅台酒股份有限公司 2022-09-13 CN claimed
WO-2022026633-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 WO claimed
EP-4746974-A1 GP130 ANTIGEN-BINDING ANTIBODIES VVB Bio Pte. Ltd. (SG) 2026-05-27 EP disclosed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
EP-4743101-A1 MUTATED ADENOVIRUSES WITH IMPROVED REPLICATION AND THEIR USE FOR TREATING CANCER Theolytics Ltd. (GB) 2026-05-20 EP disclosed
EP-4743479-A1 ADENOVIRUSES Theolytics Ltd. (GB) 2026-05-20 EP disclosed
US-12565666-B2 Methods and compositions for modulating a genome FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2026-03-03 US disclosed
US-20260047588-A1 ANIMAL FEED ADDITIVES COMPRISING POLYPEPTIDE HAVING PROTEASE ACTIVITY AND USES THEREOF NOVOZYMES A/S (DK) 2026-02-19 US disclosed
CN-114096677-A Industrial fermentation method of microbial cells using fed-batch pre-culture 巴斯夫欧洲公司 2022-02-25 CN disclosed
WO-2022026633-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 WO disclosed
WO-2022026631-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 WO disclosed
EP-0885743-A1 Assemblage for thermal dye transfer EASTMAN KODAK COMPANY (US) 1998-12-23 EP disclosed
US-5786300-A Assemblage for thermal dye transfer EASTMAN KODAK COMPANY (US) 1998-07-28 US disclosed
US-4001455-A SWEETENING COMPOSITIONS E. R. SQUIBB & SONS, INC. (US) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260047588-A1 ANIMAL FEED ADDITIVES COMPRISING POLYPEPTIDE HAVING PROTEASE ACTIVITY AND USES THEREOF PREP, VIP, CTRL PDCD1LG2 2729/4885CD274 3745/4885MME 44/4885
US-20240391958-A1 KEANUMYCINS AND USES THEREOF IN MEDICINE AND PLANT PROTECTION KARS1, KLHL20, LSS PDCD1LG2 4028/4885CD274 3921/4885MME 1482/4885
US-12565666-B2 Methods and compositions for modulating a genome RPRD2, ERN2, TPR PDCD1LG2 1836/4885CD274 2982/4885MME 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.