SCHEMBL50542

SCHEMBL50542

O=C(O)c1ccc2cc[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
HSD17B10 Q99714 2/20 1.00
KDM4E B2RXH2 2/20 1.00
ENPP2 Q13822 2/20 1.00
HPGD P15428 1/20 1.00
GHSR Q92847 2/20 0.55
TYR P14679 1/20 0.53
MAPT P10636 2/20 0.51
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
ESR1 P03372 2/20 0.50
MAPK14 Q16539 2/20 0.50
CHRNA7 P36544 1/20 0.50
SMYD3 Q9H7B4 1/20 0.49
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49
CYP2A6 P11509 1/20 0.48
AHR P35869 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4595294 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10KDM4EENPP2HPGD
SCHEMBL29583385 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10KDM4EENPP2HPGD
Hydrochloric Acid SCHEMBL1373044 0.98 ALDH1A1 (0.96) ALDH1A1HSD17B10KDM4EENPP2HPGD
Hydrazine SCHEMBL27365039 0.96 ALDH1A1 (0.93) ALDH1A1HSD17B10KDM4EENPP2HPGD
SCHEMBL16759793 0.93 ALDH1A1 (0.86) ALDH1A1HSD17B10KDM4EENPP2HPGD
Trifluoroacetic Acid SCHEMBL5740837 0.90 ALDH1A1 (0.81) ALDH1A1HSD17B10KDM4EENPP2HPGD
Indole SCHEMBL28009908 0.86 ALDH1A1 (0.73) ALDH1A1HSD17B10KDM4EENPP2HPGD
SCHEMBL2951840 0.85 KDM4E (0.74) ALDH1A1HSD17B10KDM4EENPP2HPGD
SCHEMBL105928 0.84 KDM4E (0.72) ALDH1A1HSD17B10KDM4EENPP2HPGD
Benzoic Acid SCHEMBL8915824 0.84 ALDH1A1 (0.71) ALDH1A1HSD17B10KDM4EENPP2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2076 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119979085-A Graphene conductive adhesive and preparation method thereof 深圳稀导技术有限公司 2025-05-13 CN claimed
CN-119978353-A Cation exchange graft polymer, preparation method thereof and proton exchange membrane 南阳师范学院 2025-05-13 CN claimed
CN-118727506-B Preparation process of antifouling wear-resistant protective coating and application of antifouling wear-resistant protective coating in thermosensitive paper 江苏金大包装材料科技有限公司 2025-04-25 CN claimed
CN-119822483-A Method for degrading perfluorinated compounds in sludge 广东工业大学 2025-04-15 CN claimed
CN-115920673-B High-flux aromatic polyamide reverse osmosis membrane and preparation method thereof 万华化学集团股份有限公司 2025-02-18 CN claimed
CN-118994223-A Aluminum oxide nanotube crystalline material and preparation method and application thereof 中国科学院福建物质结构研究所 2024-11-22 CN claimed
CN-118727506-A Preparation process of antifouling wear-resistant protective coating and application of antifouling wear-resistant protective coating in thermosensitive paper 江苏金大包装材料科技有限公司 2024-10-01 CN claimed
CN-118405733-A Coated ternary positive electrode material and preparation method thereof 合肥国轩高科动力能源有限公司 2024-07-30 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-115873520-B Antistatic functional adhesive tape and preparation process thereof 江西昊泽光学膜科技有限公司 2023-10-31 CN claimed
US-20030153555-A1 Novel compounds ASTRAZENECA AB (SE) 2003-08-14 US claimed
US-20030144175-A1 Protease inhibitors SMITHKLINE BEECHAM CORPORATION 2003-07-31 US claimed
US-20030044399-A1 Method of treatment SMITHKLINE BEECHAM CORPORATION 2003-03-06 US claimed
US-20030008915-A1 Acylated 6,7,8,9-tetrahydro-5H-benzocycloheptenyl amines and their use as pharmaceutical agents SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2003-01-09 US claimed
US-20020169101-A1 Treatment of sexual dysfunction WARNER-LAMBERT COMPANY 2002-11-14 US claimed
US-20020147188-A1 Protease inhibitors SMITHKLINE BEECHAM CORPORATION 2002-10-10 US claimed
WO-2002002512-A2 COMPOUNDS TO TREAT ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. (US) 2002-01-10 WO claimed
WO-1999009007-A1 SOLID PHASE SYNTHESIS OF 2,3-DISUBSTITUTED INDOLE COMPOUNDS AMERICAN HOME PRODUCTS CORPORATION (US) 1999-02-25 WO claimed
CN-1024626-C Tetrahydrobenz [c,d] indole serotonin agonists LILLY CO ELI (US) 1994-05-25 CN claimed
CN-1046330-A Tetrahydro benzo [c, d] indole serotonin stimulant LILLY CO ELI (US) 1990-10-24 CN claimed