SCHEMBL505429

SCHEMBL505429

O=C(O)C1(C(=O)O)C=CC=CC1c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 1/20 0.32
CYP2C19 P33261 2/20 0.32
MAPK1 P28482 1/20 0.32
HDAC4 P56524 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC9 Q9UKV0 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
MAPT P10636 2/20 0.31
CA2 P00918 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
EPHX1 P07099 1/20 0.31
OPRK1 P41145 1/20 0.30
POLB P06746 2/20 0.30
CYP3A4 P08684 1/20 0.30
PARP1 P09874 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7174116 0.89
SCHEMBL16599817 0.79 HTR2A (0.33) EDNRACYP2C19MAPK1HDAC4HDAC3
SCHEMBL9851147 0.78 NPC1 (0.37) MAPTKDM4EEPHX1POLBTDP1
SCHEMBL17707789 0.77 AKR1C1 (0.33) EDNRATDP1AKR1C1
SCHEMBL9858330 0.77 TSHR (0.38) MAPTKDM4EPOLBCYP3A4TSHR
SCHEMBL5170532 0.76 POLB (0.35) EDNRAMAPK1MAPTPOLBCYP3A4
SCHEMBL20520159 0.75 KDM1A (0.33) CYP2C19MAPK1MAPTKDM4EHPGD
SCHEMBL7559064 0.75 HTR2A (0.33)
SCHEMBL365626 0.75 CHRNA7 (0.32)
SCHEMBL734440 0.72 KDM1A (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478970-B Precursor composition of covalent organic framework material and application thereof 中国科学院大连化学物理研究所 2023-11-03 CN claimed
CN-109401295-B Reinforced polyamide moulding compounds having low haze and moulded bodies produced therefrom EMS专利股份公司 2023-02-03 CN claimed
CN-109401294-B Reinforced polyamide moulding compounds having low haze and moulded bodies produced therefrom EMS专利股份公司 2022-11-11 CN claimed
CN-111712530-A Polyamide moulding compound EMS专利股份公司 2020-09-25 CN claimed
US-10611954-B2 Polyamide resins for coating of sand or ceramic proppants used in hydraulic fracturing LAWTER INC. (US) 2020-04-07 US claimed
WO-2016112013-A1 POLYAMIDE RESINS FOR COATING OF SAND OR CERAMIC PROPPANTS USED IN HYDRAULIC FRACTURING LAWTER, INC. (US) 2016-07-14 WO claimed
EP-1948736-B1 PROCESS FOR PREPARING FLAKE-FORM PARTICLES BASF SE (DE) 2011-03-16 EP claimed
US-20100062244-A1 Process for Preparing Flake-Form Particles CIBA CORPORATION (US) 2010-03-11 US claimed
EP-1948736-A1 PROCESS FOR PREPARING FLAKE-FORM PARTICLES Ciba Holding Inc. (CH) 2008-07-30 EP claimed
CN-100404527-C Chiral 4,4'-dimethoxy-5,6,5',6'-bis methylene dioxy -2,2'-phthalic acid derivatives and process for preparing same QUALITY INSPECTION AND ANALYSI (CN) 2008-07-23 CN claimed
EP-1404763-B8 METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS CIBA SC HOLDING AG (CH) 2007-10-10 EP claimed
WO-2007057328-A1 PROCESS FOR PREPARING FLAKE-FORM PARTICLES CIBA HOLDING INC. (CH) 2007-05-24 WO claimed
EP-1784458-A2 PROCESS FOR PREPARING FLAKE-FORM PIGMENTS BASED ON ALUMINUM AND ON SIOZ (Z=0.7-2.0) CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-05-16 EP claimed
US-7157116-B2 Method for the production of plane-parallel platelets by using organic separating agents CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-02 US claimed
CN-1837203-A Chiral 4,4'-dimethoxy-5,6,5',6'-bis methylene dioxy -2,2'-phthalic acid derivatives and process for preparing same QUALITY INSPECTION AND ANALYSI (CN) 2006-09-27 CN claimed
WO-2006021528-A2 PROCESS FOR PREPARING FLAKE-FORM PIGMENTS BASED ON ALUMINIUM AND ON SIOZ (Z=0 . 7-2.0) CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-03-02 WO claimed
EP-1404763-B1 METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS CIBA SC HOLDING AG (CH) 2005-10-05 EP claimed
US-20040131776-A1 Method for the production of plane-parallel platelets by using organic separating agents CIBA SPECIALTY CHEMICALS CORP. 2004-07-08 US claimed
EP-1404763-A1 METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS Ciba Specialty Chemicals Holding Inc. (CH) 2004-04-07 EP claimed
WO-2002094945-A1 METHOD FOR THE PRODUCTION OF PLANE-PARALLEL PLATELETS BY USING ORGANIC SEPARATING AGENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-11-28 WO claimed