Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9851147 | 0.79 | NPC1 (0.37) | ALDH1A1SMN1; SMN2KMT2APOLBLMNA | |
| SCHEMBL505429 | 0.77 | EDNRA (0.32) | TSHRHSD17B10POLBCYP3A4MAPT | |
| SCHEMBL7174116 | 0.77 | — | — | |
| SCHEMBL5170532 | 0.72 | POLB (0.35) | TSHRHSD17B10KMT2APOLBCYP3A4 | |
| SCHEMBL8858048 | 0.70 | CYP2C19 (0.46) | ALDH1A1ALOX15HSD17B10KMT2ACYP3A4 | |
| SCHEMBL8585800 | 0.68 | ELANE (0.32) | TSHRPOLB | |
| SCHEMBL6898843 | 0.67 | — | — | |
| SCHEMBL28350465 | 0.67 | TSHR (0.37) | TSHRALDH1A1SMN1; SMN2ALOX15HSD17B10 | |
| SCHEMBL29289979 | 0.67 | HSD11B1 (0.36) | TSHRALDH1A1KMT2APOLBCYP3A4 | |
| SCHEMBL7801403 | 0.66 | TSHR (0.36) | TSHRALDH1A1SMN1; SMN2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407808-A2 | Catalyst, process for preparation of same, and process for polymerization of olefins using same | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-01-16 | — | — | EP | disclosed |