Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858330 | 0.79 | TSHR (0.38) | MAPTMEN1KMT2ALMNACES2 | |
| SCHEMBL505429 | 0.78 | EDNRA (0.32) | EPHX1MAPTPOLBKDM4ETDP1 | |
| SCHEMBL7174116 | 0.72 | — | — | |
| SCHEMBL2188570 | 0.71 | NPC1 (0.39) | NPC1RAB9AATMEPHX1GAA | |
| SCHEMBL16599817 | 0.69 | HTR2A (0.33) | LMNA | |
| SCHEMBL4979849 | 0.67 | KCNQ3 (0.34) | NPC1LMNASMN1; SMN2 | |
| SCHEMBL10480659 | 0.67 | CES2 (0.35) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4743205 | 0.67 | PTGS2 (0.33) | EPHX1MEN1KMT2ALMNAHSD11B1 | |
| SCHEMBL6231235 | 0.66 | MAOB (0.32) | — | |
| SCHEMBL11021404 | 0.66 | HSD11B1 (0.36) | NPC1RAB9AMEN1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451104-A2 | Soluble polyarylenetherketones | CIBA-GEIGY AG (CH) | 1991-10-09 | — | — | EP | disclosed |