SCHEMBL5055341

SCHEMBL5055341

O=C(O)c1ccc(O)cc1C(=O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
KDM4E B2RXH2 1/20 0.70
USP2 O75604 1/20 0.70
GAA P10253 1/20 0.70
KEAP1 Q14145 1/20 0.70
NFE2L2 Q16236 1/20 0.70
AKR1C3 P42330 2/20 0.64
POLB P06746 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CDC25B P30305 2/20 0.56
CDC25A P30304 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ALDH1A1 P00352 3/20 0.56
LMNA P02545 2/20 0.56
HPGD P15428 2/20 0.56
CYP1A2 P05177 1/20 0.56
PGR P06401 1/20 0.56
CYP2D6 P10635 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28021862 0.92 MEN1 (0.75) MEN1KMT2AKDM4EUSP2GAA
SCHEMBL7583152 0.90 TDP1 (0.72) MEN1KMT2AKDM4EUSP2GAA
Phthalic Acid SCHEMBL4885360 0.84 ALDH1A1 (0.64) MEN1KMT2AKDM4EUSP2GAA
2,4-Dihydroxybenzophenone SCHEMBL30201813 0.82 MEN1 (1.00) MEN1KMT2AKDM4EUSP2GAA
SCHEMBL29457566 0.82 MEN1 (0.72) MEN1KMT2AKDM4EUSP2GAA
SCHEMBL5527283 0.82 POLB (0.72) MEN1KMT2AKDM4EUSP2GAA
2,4-Dihydroxybenzophenone SCHEMBL29351647 0.82 MEN1 (1.00) MEN1KMT2AKDM4EUSP2GAA
SCHEMBL8442329 0.82 KDM4E (1.00) MEN1KMT2AKDM4EUSP2GAA
2,4-Dihydroxybenzophenone SCHEMBL1699129 0.82 MEN1 (1.00) MEN1KMT2AKDM4EUSP2GAA
SCHEMBL2868140 0.82 MEN1 (0.72) MEN1KMT2AKDM4EUSP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040260071-A1 Benzophene-linked crf and crf-like peptides for covalent labeling of corticotropin-releasing factor crf binding protein MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2004-12-23 US claimed
EP-1402271-A2 BENZOPHENONE-LINKED CRF AND CRF-LIKE PEPTIDES FOR COVALENT LABELING OF CORTICOTROPIN-RELEASING FACTOR (CRF) BINDING PROTEIN Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2004-03-31 EP claimed
WO-2002095395-A2 BENZOPHENONE-LINKED CRF AND CRF-LIKE PEPTIDES FOR COVALENT LABELING OF CORTICOTROPIN-RELEASING FACTOR (CRF) BINDING PROTEIN MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2002-11-28 WO claimed
US-20080221021-A1 Novel Corticotropin-Releasing Factor Receptor 1 (Crfr1) Agonist MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER (DE) 2008-09-11 US disclosed
EP-1720903-A1 CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 (CRFR1) AGONIST POLYPEPTIDES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2006-11-15 EP disclosed
US-6991874-B1 Compositions suitable for electrochemical cells BASF AKTIENGESELLSCHAFT (DE) 2006-01-31 US disclosed
WO-2005073249-A1 CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 (CRFR1) AGONIST POLYPEPTIDES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2005-08-11 WO disclosed
US-20040260071-A1 Benzophene-linked crf and crf-like peptides for covalent labeling of corticotropin-releasing factor crf binding protein MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2004-12-23 US disclosed
CN-1146588-C Compositions suitable for use in electrochemical cells BASF 2004-04-21 CN disclosed
EP-1402271-A2 BENZOPHENONE-LINKED CRF AND CRF-LIKE PEPTIDES FOR COVALENT LABELING OF CORTICOTROPIN-RELEASING FACTOR (CRF) BINDING PROTEIN Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2004-03-31 EP disclosed
US-6632561-B1 Particles and dual binder composed of crosslinkable and nonreactive polymers; high temperature dimensional stability; increased lithium ion conductivity BASF AKTIENGESELLSCHAFT (DE) 2003-10-14 US disclosed
EP-1138092-A1 COMPOSITE BODIES USED AS SEPARATORS IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2001-10-04 EP disclosed
CN-1308642-A Compositions suitable for use in electrochemical cells BASF AG (DE) 2001-08-15 CN disclosed
EP-1109841-A1 COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2001-06-27 EP disclosed
EP-1088007-A1 COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2001-04-04 EP disclosed
WO-2000026977-A1 COMPOSITE BODIES USED AS SEPARATORS IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2000-05-11 WO disclosed
US-6031044-A A WATER-SOLUBLE, WATER-DISPERSIBLE POLYURETHANE COPOLYMER HAVING PHOTOINITIATOR UNITS BONDED COVALENTLY TO THE POLYMER CHAIN; CROSSLINKABLE BY IRRADIATION WITH UV LIGHT AFTER DRYING; PROTECTIVE COATINGS BASF AKTIENGESELLSCHAFT (DE) 2000-02-29 US disclosed
WO-2000008068-A1 COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2000-02-17 WO disclosed
WO-1999057161-A1 COMPOSITIONS SUITABLE FOR ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 1999-11-11 WO disclosed
EP-0849300-A1 Polyurethanes with covalently bound photoinitiator-units BASF AKTIENGESELLSCHAFT (DE) 1998-06-24 EP disclosed