Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 9/20 | 0.68 |
| ▸ | ITPR1 | Q14643 | 5/20 | 0.68 |
| ▸ | ITPR2 | Q14571 | 4/20 | 0.68 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.59 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171543 | 0.96 | ITPR3 (0.60) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL11233751 | 0.96 | ITPR3 (0.60) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL6664274 | 0.96 | ITPR3 (0.74) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL14992390 | 0.94 | ITPR3 (0.61) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL7117013 | 0.92 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL9165530 | 0.92 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL462454 | 0.92 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL1356398 | 0.92 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL4343592 | 0.92 | ITPR3 (0.74) | ITPR3ITPR1ITPR2INPP5AINPPL1 | |
| SCHEMBL639515 | 0.92 | ITPR3 (0.54) | ITPR3ITPR1ITPR2INPP5AINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080063637-A1 | Regulation of oncogenesis by Akt-specific isoforms | THE TRUSTEES OF TUFTS COLLEGE | 2008-03-13 | — | — | US | disclosed |