⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941982 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL14865953 | 0.79 | — | — | |
| SCHEMBL13941987 | 0.73 | — | — | |
| SCHEMBL1471395 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL12879482 | 0.71 | — | — | |
| SCHEMBL18056864 | 0.69 | — | — | |
| SCHEMBL10613633 | 0.69 | — | — | |
| SCHEMBL28751396 | 0.69 | LMNA (0.30) | — | |
| SCHEMBL16602995 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL10524658 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640526-B2 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-05-05 | — | — | US | disclosed |
| US-20180319833-A1 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-11-08 | — | — | US | disclosed |
| EP-3377508-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2018-09-26 | — | — | EP | disclosed |
| EP-3170832-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2017-05-24 | — | — | EP | disclosed |
| CN-102388014-A | Synthesis method of chiral alpha-aryl propionic acid derivative | DSM IP ASSETS BV | 2012-03-21 | — | — | CN | disclosed |
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | disclosed |
| EP-2393771-A1 | Method for the synthesis of chiral alpha-aryl propionic acid derivatives | DSM IP Assets B.V. (NL) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089343-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2010-08-12 | — | — | WO | disclosed |