SCHEMBL1471395

SCHEMBL1471395

CC(C)[Si](CCO)(C(C)C)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064414 0.78
SCHEMBL622662 0.72 TSHR (0.38) TSHRTDP1
SCHEMBL505851 0.71
SCHEMBL11860637 0.69
SCHEMBL8062669 0.67
SCHEMBL13431360 0.67 LMNA (0.32)
SCHEMBL17165761 0.67
SCHEMBL15914659 0.65 TSHR (0.35) TSHR
SCHEMBL19543062 0.63 LMNA (0.41)
SCHEMBL20672949 0.63 NFKB1 (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102197055-A Curable composition for transfer material and pattern formation method SHOWA DENKO KK 2011-09-21 CN claimed
US-20110206834-A1 CURABLE COMPOSITION FOR TRANSFER MATERIALS, AND PATTERN FORMING PROCESS SHOWA DENKO K.K. (JP) 2011-08-25 US claimed
EP-2345676-A1 CURABLE COMPOSITION FOR TRANSFER MATERIAL AND PATTERN FORMATION METHOD SHOWA DENKO K.K. (JP) 2011-07-20 EP claimed
US-10640526-B2 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2020-05-05 US disclosed
US-20180319833-A1 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2018-11-08 US disclosed
EP-3377508-A1 METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE Centre National De La Recherche Scientifique (FR) 2018-09-26 EP disclosed
EP-3170832-A1 METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE Centre National De La Recherche Scientifique (FR) 2017-05-24 EP disclosed
EP-1799694-B1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE DOW CORNING TORAY CO LTD (JP) 2012-05-09 EP disclosed
CN-102197055-A Curable composition for transfer material and pattern formation method SHOWA DENKO KK 2011-09-21 CN disclosed
US-20110206834-A1 CURABLE COMPOSITION FOR TRANSFER MATERIALS, AND PATTERN FORMING PROCESS SHOWA DENKO K.K. (JP) 2011-08-25 US disclosed
EP-2345676-A1 CURABLE COMPOSITION FOR TRANSFER MATERIAL AND PATTERN FORMATION METHOD SHOWA DENKO K.K. (JP) 2011-07-20 EP disclosed
US-7915439-B2 Method of producing silylalkoxymethyl halide DOW CORNING TORAY COMPANY, LTD. (JP) 2011-03-29 US disclosed
US-20090203932-A1 Method of Producing Silylalkoxymethyl Halide DOW CORNING TORAY CO., LTD. (JP) 2009-08-13 US disclosed
EP-1799694-A1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE Dow Corning Toray Co., Ltd. (JP) 2007-06-27 EP disclosed
WO-2006040964-A1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE DOW CORNING TORAY CO., LTD. (JP) 2006-04-20 WO disclosed
US-6143724-A USED FOR TREATMENT, IMPROVEMENT AND PREVENTION OF INFLAMMATION AND DISEASES ACCOMPANYING INFLAMATION DAIKIN INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-1013660-A1 2-FLUOROFUCOSYL-N-AROYLGLUCOSAMINE DERIVATIVES, INTERMEDIATES THEREFOR, AND PROCESSES FOR PRODUCING THESE Daikin Industries, Limited (JP) 2000-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203932-A1 Method of Producing Silylalkoxymethyl Halide CBR3, CBR1, HRH3 TSHR 505/4885TDP1 4494/4885
US-10640526-B2 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose ST6GAL1, B4GALT1, GALNT6 TSHR 191/4885TDP1 2029/4885
US-20180319833-A1 Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose ST6GAL1, B4GALT1, GALNT6 TSHR 191/4885TDP1 2029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.