Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 5/20 | 0.51 |
| ▸ | CES1 | P23141 | 5/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL3991688 | 0.93 | CES2 (0.54) | CA2CA4CES2CES1NAAA | |
| Terephthalic Acid SCHEMBL28928411 | 0.91 | CA2 (0.44) | CA2CA4CES2CES1 | |
| Benzoic Acid SCHEMBL11830366 | 0.89 | CA2 (0.59) | CA2CA4CES2CES1NAAA | |
| 4-Methylbenzoic Acid SCHEMBL27922308 | 0.84 | L3MBTL1 (0.45) | CA2CES2CES1LMNAALDH1A1 | |
| Phthalic Acid SCHEMBL48951 | 0.84 | TSHR (0.44) | CA2CES2CES1NAAALMNA | |
| SCHEMBL7625372 | 0.83 | CES2 (0.54) | CA2CA4CES2CES1NAAA | |
| SCHEMBL7625362 | 0.83 | CES2 (0.54) | CA2CA4CES2CES1NAAA | |
| Benzoic Acid SCHEMBL10440245 | 0.82 | CA2 (0.47) | CA2CA4CES2CES1NAAA | |
| SCHEMBL9073817 | 0.82 | ERCC5 (0.50) | CES2CES1NAAALMNAALDH1A1 | |
| Toluene SCHEMBL28340909 | 0.81 | CES2 (0.42) | CES2CES1NAAALMNAPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119055555-A | PEG-PLA copolymer composite solution, preparation method and application thereof | 渼颜空间(河北)生物科技有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-118976148-A | Injectable filling microsphere, injectable filling material containing injectable filling microsphere, and preparation and application of injectable filling microsphere | 北京渼颜空间生物医药有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118976147-A | Injectable filling microsphere, preparation containing injectable filling microsphere, preparation method and application of injectable filling microsphere | 北京渼颜空间生物医药有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118834377-A | PLA-PEG-PLA block copolymer, injectable filling microsphere, and preparation method and application thereof | 北京渼颜空间生物医药有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-113242897-B | Adhesive agent | 美国陶氏有机硅公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118027886-A | Double-component organic silicon sealant for photovoltaic module and preparation method thereof | 杭州之江有机硅化工有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-116285596-B | Preparation method and application of anti-shrinkage cathode electrophoretic coating | 广东科德环保科技股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| US-11926708-B1 | Fluorosilicone compositions and methods related thereto | NUSIL TECHNOLOGY LLC (US) | 2024-03-12 | — | — | US | claimed |
| EP-3673027-B1 | DUAL CURE ADHESIVE COMPOSITION AND METHODS FOR ITS PREPARATION AND USE | DOW SILICONES CORP (US) | 2023-11-01 | — | — | EP | claimed |
| CN-116376498-A | Adhesive agent | 美国陶氏有机硅公司 | 2023-07-04 | — | — | CN | claimed |
| EP-0688827-A2 | Method of preparing in situ reinforced silicone elastomer | DOW CORNING CORPORATION (US) | 1995-12-27 | — | — | EP | claimed |
| US-5468829-A | In-situ reinforced silicone elastomer using resin precursor | DOW CORNING CORPORATION (US) | 1995-11-21 | — | — | US | claimed |
| US-5395908-A | Method of preparing in situ reinforced silicone elastomer | DOW CORNING CORPORATION (US) | 1995-03-07 | — | — | US | claimed |
| EP-0509437-B1 | Electrocoating composition | KANSAI PAINT CO LTD (JP) | 1995-01-25 | — | — | EP | claimed |
| US-5330839-A | Electrocoating composition containing blocked isocyanate, dialkyltin aromatic carboxylate and a bismuth or zirconium compound | KANSAI PAINT CO., LTD. (JP) | 1994-07-19 | — | — | US | claimed |
| US-5260348-A | Chainstopped polysiloxane, a crosslinking agent and an onium catalyst | GENERAL ELECTRIC COMPANY (US) | 1993-11-09 | — | — | US | claimed |
| US-5213899-A | ROOM TEMPERATURE VULCANIZABLE SILICONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 1993-05-25 | — | — | US | claimed |
| EP-0509437-A1 | Electrocoating composition | KANSAI PAINT CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4973737-A | ORGANOTIN OR ORGANOTITANATE CATALYST, BY-PRODUCT INHIBITION | KABUSHIKI KAISHA VENO SEIYAKU OYO KENKYUO (JP) | 1990-11-27 | — | — | US | claimed |
| US-4461867-A | CONTAINING A DIORGANOCYCLOPOLYSILOXANE COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1984-07-24 | — | — | US | claimed |