Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477054 | 0.89 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1LMNAKMT2A | |
| SCHEMBL26836 | 0.89 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1LMNAKMT2A | |
| SCHEMBL8746207 | 0.89 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1LMNAKMT2A | |
| SCHEMBL66196 | 0.89 | LMNA (0.59) | ALDH1A1LMNAKMT2ASMN1; SMN2CA1 | |
| SCHEMBL6114756 | 0.86 | LMNA (0.56) | ALDH1A1LMNAKMT2ASMN1; SMN2CA1 | |
| Fluoride SCHEMBL11757338 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CYP3A4MAPK1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL1328015 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CYP3A4MAPK1LMNAKMT2A | |
| SCHEMBL6909666 | 0.86 | LMNA (0.56) | ALDH1A1LMNAKMT2ASMN1; SMN2CA1 | |
| SCHEMBL6908827 | 0.86 | ALDH1A1 (0.59) | ALDH1A1CYP3A4MAPK1LMNAKMT2A | |
| SCHEMBL6916646 | 0.86 | LMNA (0.56) | ALDH1A1LMNAKMT2ASMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350009-B1 | SULFONATE SALTS OF FLUPIRTINE | TEVA GMBH (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-8222282-B2 | Sulfonate salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine | TEVA PHARMACEUTICALS USA, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20120028930-A1 | FLUPIRTINE SALTS AND POLYMORPHS | BIONEVIA PHARMACEUTICALS INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20090318506-A1 | Sulfonate salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine | AWD. PHARMA GMBH & CO. KG (DE) | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318506-A1 | Sulfonate salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine | SSTR3, NPSR1, SSTR2 | BRAF 638/4885ALDH1A1 1853/4885EGFR 795/4885 |
| US-20120028930-A1 | FLUPIRTINE SALTS AND POLYMORPHS | SULT2A1, TACR1, NPSR1 | BRAF 732/4885ALDH1A1 1002/4885EGFR 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.