Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467714 | 0.81 | GABRA1 (0.54) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL11504087 | 0.78 | GABRA1 (0.62) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL30195663 | 0.78 | GABRA1 (0.62) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL20235587 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL18702995 | 0.76 | TSHR (0.44) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL196228 | 0.76 | GABRA1 (0.59) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL28219025 | 0.74 | PTPN2 (0.42) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL7782324 | 0.74 | GABRA1 (0.56) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL38665354 | 0.73 | TSHR (0.50) | GABRA1GABRB2TSHRCA2LMNA | |
| SCHEMBL16809557 | 0.73 | TSHR (0.50) | GABRA1GABRB2TSHRCA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002435-A1 | VISCOELASTIC FOAMS WITH SLOWER RECOVERY AND IMPROVED TEAR | BAYER MATERIALSCIENCE LLC (US) | 2008-01-03 | — | — | WO | disclosed |
| EP-1873179-A1 | Viscoelastic foams with slower recovery and improved tear | Bayer MaterialScience LLC (US) | 2008-01-02 | — | — | EP | disclosed |
| US-20070299153-A1 | Viscoelastic foams with slower recovery and improved tear | COVESTRO LLC | 2007-12-27 | — | — | US | disclosed |
| US-4192959-A | COUNTERCURRENT EXTRACTION | HAARMANN & REIMER (DE) | 1980-03-11 | — | — | US | disclosed |