SCHEMBL467714

SCHEMBL467714

COC(O)c1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.54
GABRB2 P47870 2/20 0.54
TSHR P16473 5/20 0.48
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
TP53 P04637 2/20 0.43
LMNA P02545 4/20 0.39
CYP3A4 P08684 3/20 0.39
HPGD P15428 3/20 0.39
ALDH1A1 P00352 3/20 0.39
POLB P06746 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CA12 O43570 2/20 0.39
CA14 Q9ULX7 2/20 0.39
BLM P54132 2/20 0.39
HIF1A Q16665 2/20 0.39
TDP1 Q9NUW8 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18892781 0.85 GABRA1 (0.39) GABRA1GABRB2TSHRCA2CA1
SCHEMBL5061024 0.81 GABRA1 (0.52) GABRA1GABRB2TSHRCA2CA1
SCHEMBL18717048 0.81 TRPA1 (0.45) GABRA1GABRB2TSHRCA2CA1
SCHEMBL5142961 0.79 GABRA1 (0.56) GABRA1GABRB2TSHRCA2CA1
SCHEMBL9755150 0.79 GABRA1 (0.56) GABRA1GABRB2TSHRCA2CA1
SCHEMBL30314538 0.79 GABRA1 (0.56) GABRA1GABRB2TSHRCA2CA1
SCHEMBL4624282 0.78 GABRA1 (0.50) GABRA1GABRB2TSHRCA2CA1
SCHEMBL6204702 0.77 GABRA1 (0.48) GABRA1GABRB2TSHRCA2CA1
SCHEMBL6203758 0.77 CA1 (0.52) TSHRCA2CA1TP53LMNA
SCHEMBL1755231 0.77 ESR1 (0.52) GABRA1GABRB2TSHRLMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1649029-B1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT PLANT SECONDARY METABOLITE IN A YEAST CELL EVOLVA SA (CH) 2014-12-17 EP claimed
EP-3197460-B1 DERMOCOSMETIC OR PHARMACEUTICAL USE OF A COMPOSITION CONTAINING AT LEAST ONE INHIBITOR OF CERTAIN CHEMOKINES GREENPHARMA SAS (FR) 2022-04-20 EP disclosed
US-10617144-B2 Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles R.J. REYNOLDS TOBACCO COMPANY (US) 2020-04-14 US disclosed
EP-2709476-B1 MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES REYNOLDS TOBACCO CO R (US) 2016-09-21 EP disclosed
US-20160044957-A1 MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES R.J. REYNOLDS TOBACCO COMPANY 2016-02-18 US disclosed
US-20160044957-A1 MOLECULARLY IMPRINTED POLYMERS FOR TREATING TOBACCO MATERIAL AND FILTERING SMOKE FROM SMOKING ARTICLES R.J. REYNOLDS TOBACCO COMPANY 2016-02-18 US disclosed
US-9192193-B2 Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles R.J. REYNOLDS TOBACCO COMPANY (US) 2015-11-24 US disclosed
US-9192193-B2 Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles R.J. REYNOLDS TOBACCO COMPANY (US) 2015-11-24 US disclosed
US-20150232889-A1 Method of Producing a Low Molecular Weight Organic Compound in a Cell EVOLVA SA (CH) 2015-08-20 US disclosed
US-8986950-B2 Method of producing a low molecular weight organic compound in a cell EVOLVA SA (CH) 2015-03-24 US disclosed
US-20110318793-A1 Method of Producing a Low Molecular Weight Organic Compound in a Cell EVOLVA SA (CH) 2011-12-29 US disclosed
EP-2388333-A2 A method of producing a low molecular weight organic compound in a cell Evolva SA (CH) 2011-11-23 EP disclosed
US-8041750-B2 Method and apparatus for organizing and playing data YAHOO! INC. (US) 2011-10-18 US disclosed
US-20110136177-A1 Method of Producing a Low Molecular Weight Organic Compound in a Cell BLMaps (DK) 2011-06-09 US disclosed
US-7846697-B2 Method of producing a low molecular weight organic compound in a cell BLMaps (DK) 2010-12-07 US disclosed
US-20060275877-A1 Method of producing a low molecular weight organic compound in a cell DANSTAR FERMENT AG (CH) 2006-12-07 US disclosed
EP-1649029-A1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT ORGANIC COMPOUND IN A CELL Poalis A/S (DK) 2006-04-26 EP disclosed
EP-1510586-A1 A method of producing a low molecular weight organic compound in a cell Poalis A/S (DK) 2005-03-02 EP disclosed
WO-2004111254-A1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT ORGANIC COMPOUND IN A CELL POALIS A/S (DK) 2004-12-23 WO disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed