Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.52 |
| ▸ | HNF4A | P41235 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.49 |
| ▸ | FEN1 | P39748 | 2/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.46 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120353 | 0.86 | ACMSD (0.63) | ESR2ACMSDHNF4AAKR1C2AKR1C1 | |
| SCHEMBL11037121 | 0.84 | ACMSD (0.55) | ESR2ACMSDHNF4AAKR1C2AKR1C1 | |
| SCHEMBL11150735 | 0.83 | ESR2 (0.53) | ESR2ACMSDHNF4AAKR1C2AKR1C1 | |
| SCHEMBL27803956 | 0.81 | CDC25B (0.53) | ESR2ACMSDHNF4AAKR1C2AKR1C1 | |
| SCHEMBL10623435 | 0.81 | ESR2 (0.52) | ESR2ACMSDHNF4AAKR1C2AKR1C1 | |
| SCHEMBL11476855 | 0.80 | ERCC5 (0.42) | AKR1C2AKR1C1HDAC8HDAC6ERCC5 | |
| SCHEMBL4864533 | 0.79 | ALDH1A1 (0.57) | ACMSDHNF4AAKR1C2AKR1C1DHFR | |
| SCHEMBL10911662 | 0.79 | RXRB (0.50) | ACMSDHNF4AMKNK1MKNK2DHFR | |
| SCHEMBL6502082 | 0.79 | PDK2 (0.57) | ESR2HDAC8HDAC6ERCC5FEN1 | |
| SCHEMBL28184683 | 0.78 | AVPR2 (0.50) | ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103635837-A | Polarizing photochromic articles | TRANSITIONS OPTICAL INC | 2014-03-12 | — | — | CN | disclosed |
| CN-101727004-B | Photoacid generator containing aromatic ring | KOREA KUMHO PETROCHEM CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-102934011-A | Liquid crystal alignment agent containing end-modified polyamic acid ester, and liquid crystal alignment film | NISSAN CHEMICAL IND LTD | 2013-02-13 | — | — | CN | disclosed |
| CN-102893206-A | Liquid crystal alignment agent containing end-modified polyamic acid ester, and liquid crystal alignment film | NISSAN CHEMICAL IND LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-101727004-A | Photoacid generator containing aromatic ring | KOREA KUMHO PETROCHEM CO LTD | 2010-06-09 | — | — | CN | disclosed |
| CN-100416302-C | Thermoplastic norbornene resin based optical film | JSR CORP (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-100416314-C | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL INC (US) | 2008-09-03 | — | — | CN | disclosed |
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1867639-A1 | UREA DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| CN-1842730-A | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL INC (US) | 2006-10-04 | — | — | CN | disclosed |
| CN-1608214-A | Thermoplastic norbornene resin based optical film | JSR CORP (JP) | 2005-04-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | AVPR2, UTS2R, GPR119 | ESR2 362/4885ACMSD 1754/4885HNF4A 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.