SCHEMBL5063473

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3783986	0.86	PYGL (0.57)	HPGDPYGLALDH1A1MAPTKDM4E
	SCHEMBL69263	0.86	KDM4E (0.62)	HPGDALDH1A1MAPTKDM4EGLA
	SCHEMBL1483700	0.85	MAPT (0.59)	HPGDALDH1A1S1PR1S1PR3MAPT
	SCHEMBL2890548	0.84	KDM4E (0.51)	HPGDALDH1A1S1PR1S1PR3MAPT
	SCHEMBL29606273	0.83	TSHR (0.55)	HPGDPYGLALDH1A1S1PR1S1PR3
	SCHEMBL1483403	0.83	TSHR (0.55)	HPGDPYGLALDH1A1S1PR1S1PR3
	SCHEMBL16957205	0.83	KDM4E (0.50)	HPGDALDH1A1S1PR1S1PR3MAPT
	SCHEMBL12268010	0.83	KDM4E (0.50)	HPGDALDH1A1MAPTKDM4EGLA
	SCHEMBL6243384	0.83	KDM4E (0.50)	HPGDALDH1A1S1PR1S1PR3MAPT
	SCHEMBL3116280	0.83	MAPT (0.50)	HPGDALDH1A1S1PR1S1PR3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.