Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773709 | 0.83 | CYP3A4 (0.48) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL4005448 | 0.82 | KMT2A (0.52) | MEN1KMT2ALMNAHTTGPR35 | |
| SCHEMBL823689 | 0.82 | MAPT (0.41) | MEN1KMT2ALMNAGPR35ALDH1A1 | |
| SCHEMBL11309191 | 0.77 | GPR35 (0.46) | MEN1KMT2ALMNAGPR35ALDH1A1 | |
| SCHEMBL19071929 | 0.77 | CYP4F2 (0.44) | MEN1KMT2ALMNAGPR35ALDH1A1 | |
| SCHEMBL377595 | 0.74 | MAPK1 (0.51) | MEN1KMT2ALMNAGPR35ALDH1A1 | |
| SCHEMBL823830 | 0.73 | ALDH1A1 (0.50) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL18328830 | 0.73 | GPR35 (0.49) | MEN1KMT2AGPR35ALDH1A1TTR | |
| SCHEMBL19425974 | 0.73 | MAPT (0.42) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL11536853 | 0.73 | GPR35 (0.74) | MEN1KMT2ALMNAHTTGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911683-A1 | ANTIBODY | King's College London (GB) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020148425-A1 | ANTIBODY | KING'S COLLEGE LONDON (GB) | 2020-07-23 | — | — | WO | disclosed |
| US-20080206754-A1 | Method for producing monoclonal antibodies | WYETH | 2008-08-28 | — | — | US | disclosed |
| US-7247475-B2 | Method for producing monoclonal antibodies | WYETH (US) | 2007-07-24 | — | — | US | disclosed |
| US-20060141574-A1 | Method for producing monoclonal antibodies | WYETH | 2006-06-29 | — | — | US | disclosed |
| US-20060099641-A1 | Method of making libraries and anti-ligands | BIOINVENT INTERNATIONAL AB (SE) | 2006-05-11 | — | — | US | disclosed |
| US-7011974-B2 | Method for producing monoclonal antibodies | WYETH (US) | 2006-03-14 | — | — | US | disclosed |
| EP-1470225-A1 | METHOD OF MAKING LIBRARIES OF ANTI-LIGANDS | Bioinvent International AB (SE) | 2004-10-27 | — | — | EP | disclosed |
| US-20030153039-A1 | Method for producing monoclonal antibodies | WYETH (US) | 2003-08-14 | — | — | US | disclosed |
| WO-2003064648-A1 | METHOD OF MAKING LIBRARIES OF ANTI-LIGANDS | BIOINVENT INTERNATIONAL AB (SE) | 2003-08-07 | — | — | WO | disclosed |
| US-6475787-B1 | Method for producing monoclonal antibodies | WYETH | 2002-11-05 | — | — | US | disclosed |
| US-6027735-A | IMPROVING NUTRIENT UTILIZATION IN AN ANIMAL OR HUMAN BY IMMUNIZING ORALLY OR PARENTERALLY WITH AN ANTIGEN TO INITIATING DIGESTION, STIMULATING THE SECRETION OF DIGESTIVE ACIDS AND ENZYMES, INCREASING THE BLOOD FLOW AND STIMULATING | EFFEM GMBH (DE) | 2000-02-22 | — | — | US | disclosed |
| US-5965605-A | ANTAGONIZING INTERACTION BETWEEN IMMUNOGLOBIN E AND ITS RECEPTOR FC.EPSILON.RI ON SURFACE OF MAMMALIAN CELL BY ADMINISTERING ANTAGONIZING AMOUNT OF TETRACYCLIC COMPOUND TO PREVENT ALLERGIC RESPONSES | HESKA CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5725861-A | Products and processes for gastric cascade and gastrointestinal disorder treatment with same | EFFEM GMBH (DE) | 1998-03-10 | — | — | US | disclosed |
| WO-1997040033-A1 | INHIBITION OF THE BINDING OF HUMAN IGE TO ITS RECEPTOR BY TETRACYCLIC COMPOUNDS FOR THE ALLEVIATION OF IGE-MEDIATED IMMUNE RESPONSE | LEXIGEN PHARMACEUTICALS CORP. (US) | 1997-10-30 | — | — | WO | disclosed |
| EP-0483194-B1 | IgG3 ANTIBODIES WITH SHORTENED HINGE REGION AND A COMPLEMENT ACTIVATION TEST | DYNAL AS (NO) | 1996-04-17 | — | — | EP | disclosed |
| US-5348876-A | DNA molecules and codes with polypeptide sequences | DYNAL AS (NO) | 1994-09-20 | — | — | US | disclosed |
| EP-0483194-A1 | IgG3 ANTIBODIES WITH SHORTENED HINGE REGION AND A COMPLEMENT ACTIVATION TEST. | DYNAL AS (NO) | 1992-05-06 | — | — | EP | disclosed |
| WO-1991001335-A1 | IgG3 ANTIBODIES WITH SHORTENED HINGE REGION AND A COMPLEMENT ACTIVATION TEST | DYNAL A.S. (NO) | 1991-02-07 | — | — | WO | disclosed |
| EP-0267779-A2 | Human pleiotropic immune factor and muteins thereof | Schering Biotech Corporation (US) | 1988-05-18 | — | — | EP | disclosed |