Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728948 | 0.87 | HRH3 (0.48) | HRH3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5067350 | 0.81 | RAB9A (0.43) | HRH3NPC1RAB9ABCHEACHE | |
| SCHEMBL5148486 | 0.79 | HRH3 (0.46) | HRH3 | |
| SCHEMBL5070305 | 0.78 | CETP (0.43) | HRH3NPC1RAB9ATHRBTHRA | |
| SCHEMBL1779706 | 0.76 | HRH3 (0.59) | HRH3ALDH1A1LMNA | |
| SCHEMBL5070282 | 0.76 | TRPV4 (0.42) | HRH3NPC1RAB9ATHRBTHRA | |
| SCHEMBL5069481 | 0.76 | CETP (0.41) | HRH3NPC1RAB9ATHRBTHRA | |
| SCHEMBL727538 | 0.76 | HRH3 (0.45) | HRH3THRBTHRASMN1; SMN2KDM4E | |
| SCHEMBL727795 | 0.74 | HRH3 (0.46) | HRH3THRBTHRAACHEALDH1A1 | |
| SCHEMBL727691 | 0.73 | HRH3 (0.48) | HRH3KMT2ATHRBTHRASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979334-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong Wha Pharmaceutical. Ind. Co., Ltd. (KR) | 2008-10-15 | — | — | EP | claimed |
| WO-2007089101-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG WHA PHARMACEUTICAL IND.CO., LTD. (KR) | 2007-08-09 | — | — | WO | claimed |