Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727889 | 0.85 | HRH3 (0.46) | HRH3AGERKCNH2HRH4 | |
| SCHEMBL5070305 | 0.81 | CETP (0.43) | HRH3HRH2HRH1 | |
| SCHEMBL5069481 | 0.79 | CETP (0.41) | HRH3HRH2HRH1 | |
| SCHEMBL5064006 | 0.79 | HRH3 (0.46) | HRH3 | |
| SCHEMBL5070282 | 0.78 | TRPV4 (0.42) | HRH3HRH2HRH1KCNH2 | |
| SCHEMBL727597 | 0.76 | CETP (0.46) | HRH3KCNH2 | |
| SCHEMBL7293962 | 0.76 | HRH3 (0.62) | HRH3HRH2HRH1KCNH2 | |
| SCHEMBL727795 | 0.75 | HRH3 (0.46) | HRH3KCNH2 | |
| SCHEMBL727955 | 0.75 | BMPR1B (0.43) | HRH3KCNH2 | |
| SCHEMBL5067350 | 0.74 | RAB9A (0.43) | HRH3CHEK2AGERKCNH2HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979334-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Dong Wha Pharmaceutical. Ind. Co., Ltd. (KR) | 2008-10-15 | — | — | EP | claimed |
| WO-2007089101-A1 | NOVEL BENZAMIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONG WHA PHARMACEUTICAL IND.CO., LTD. (KR) | 2007-08-09 | — | — | WO | claimed |