Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28413060 | 1.00 | PAOX (0.38) | PAOXLMNACYP1A2THRBBLM | |
| Acetic Acid SCHEMBL3253044 | 1.00 | PAOX (0.38) | PAOXLMNACYP1A2THRBBLM | |
| Acetic Acid SCHEMBL28413059 | 1.00 | PAOX (0.38) | PAOXLMNACYP1A2THRBBLM | |
| Acetic Acid SCHEMBL3255424 | 0.94 | PAOX (0.41) | PAOXLMNACYP1A2THRBBLM | |
| Acetone SCHEMBL2390270 | 0.93 | PAOX (0.39) | PAOXLMNACYP1A2THRBBLM | |
| Bicarbonate SCHEMBL18662974 | 0.93 | LMNA (0.37) | PAOXLMNACYP1A2THRBBLM | |
| Acetic Acid SCHEMBL4300678 | 0.89 | PAOX (0.40) | PAOXLMNACYP1A2KMT2AMEN1 | |
| Urea SCHEMBL27918835 | 0.89 | PAOX (0.34) | PAOXLMNACYP1A2THRBBLM | |
| Methacrylic Acid SCHEMBL1548074 | 0.88 | PAOX (0.33) | PAOXLMNACYP1A2THRBBLM | |
| Butanone SCHEMBL8850665 | 0.88 | ALDH1A1 (0.40) | PAOXLMNACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361275-B2 | Use of derivatized nanoparticles to minimize growth of micro-organisms in hot filled drinks | EASTMAN KODAK COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7357979-B2 | Composition of matter comprising polymer and derivatized nanoparticles | EASTMAN KODAK COMPANY (US) | 2008-04-15 | — | — | US | disclosed |
| US-7311933-B2 | Packaging material for inhibiting microbial growth | EASTMAN KODAK COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| WO-2006075995-A2 | ARTICLE INHIBITING MICROBIAL GROWTH IN PHYSIOLOGICAL FLUIDS | EASTMAN KODAK COMPANY (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2005111129-A2 | COMPOSITION COMPRISING POLYMER AND DERIVATIZED NANOPARTICLES | EASTMAN KODAK COMPANY (US) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005107501-A2 | ARTICLE FOR INHIBITING MICROBIAL GROWTH | EASTMAN KODAK COMPANY (US) | 2005-11-17 | — | — | WO | disclosed |
| WO-2005099489-A2 | MINIMIZING GROWTH OF MICRO-ORGANISMS IN LIQUID NUTRIENTS BY LIMITATION OF ESSENTIAL METAL IONS | EASTMAN KODAK COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050226913-A1 | Article for inhibiting microbial growth in physiological fluids | EASTMAN KODAK COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050228099-A1 | Composition of matter comprising polymer and derivatized nanoparticles | EASTMAN KODAK COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050224419-A1 | Use of derivatized nanoparticles to minimize growth of micro-organisms in hot filled drinks | EASTMAN KODAK COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050224417-A1 | Use of derivatized nanoparticles to minimize growth of micro-organisms in hot filled drinks | EASTMAN KODAK COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050226911-A1 | Article for inhibiting microbial growth in physiological fluids | EASTMAN KODAK COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050226966-A1 | Article for inhibiting microbial growth | QUALEX INC. | 2005-10-13 | — | — | US | disclosed |
| US-20050226967-A1 | Article for inhibiting microbial growth | EASTMAN KODAK COMPANY | 2005-10-13 | — | — | US | disclosed |
| US-20050224416-A1 | Use of derivatized nanoparticles to minimize growth of micro-organisms in hot filled drinks | NPEC INC. | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050226913-A1 | Article for inhibiting microbial growth in physiological fluids | FABP2, FABP1, MIF | PAOX 1000/4885LMNA 4542/4885CYP1A2 2620/4885 |
| US-20050226911-A1 | Article for inhibiting microbial growth in physiological fluids | FABP2, FABP1, FABP6 | PAOX 748/4885LMNA 4514/4885CYP1A2 2664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.