Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067753 | 0.88 | CA2 (0.46) | TSHRGRIK1GRIK2CPA1SLC1A3 | |
| SCHEMBL10457723 | 0.86 | CA2 (0.44) | TSHRGRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL5363929 | 0.84 | CHRM1 (0.46) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL7990541 | 0.84 | GRIK1 (0.45) | TSHRGRIK1GRIK2CPA1ALDH1A1 | |
| SCHEMBL14471116 | 0.83 | HDAC7 (0.45) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| 4-En-Metabolite SCHEMBL1000796 | 0.83 | CHRM1 (0.62) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| 4-En-Metabolite SCHEMBL9111371 | 0.83 | CHRM1 (0.62) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL1728215 | 0.82 | — | — | |
| SCHEMBL17343614 | 0.81 | CA1 (0.45) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL22306014 | 0.81 | CA1 (0.45) | HDAC7HDAC8HDAC6HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312112-A1 | Lubricating formulations for dispersancy and temperature, friction, and wear reduction | LYON DEVELOPMENT CORPORATION | 2008-12-18 | — | — | US | disclosed |