Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457723 | 0.94 | CA2 (0.44) | CA2CA1MAPK1ALDH1A1SLC1A2 | |
| SCHEMBL5065618 | 0.88 | HDAC7 (0.45) | CA2CA1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3968081 | 0.86 | CA2 (0.47) | CA2CA1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL570260 | 0.84 | CA2 (0.61) | CA2CA1MAPK1SLC1A3SLC1A2 | |
| SCHEMBL2081268 | 0.84 | CA2 (0.61) | CA2CA1MAPK1SLC1A3SLC1A2 | |
| SCHEMBL8572261 | 0.82 | CA2 (0.59) | CA2CA1MAPK1SLC1A3SLC1A2 | |
| SCHEMBL5805533 | 0.82 | CA2 (0.44) | CA2CA1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL5197384 | 0.82 | CA2 (0.44) | CA2CA1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL28191059 | 0.82 | CA2 (0.62) | CA2CA1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL8567555 | 0.82 | CA2 (0.59) | CA2CA1MAPK1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312112-A1 | Lubricating formulations for dispersancy and temperature, friction, and wear reduction | LYON DEVELOPMENT CORPORATION | 2008-12-18 | — | — | US | disclosed |