Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402734 | 0.94 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL5150650 | 0.91 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL21810823 | 0.91 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL25268394 | 0.88 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL26264750 | 0.87 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL10004653 | 0.87 | SMYD2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL5027948 | 0.85 | TRPA1 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2TRPA1 | |
| SCHEMBL26103074 | 0.85 | SLC6A2 (0.39) | SMYD2CYP3A4HTTSMN1; SMN2RIPK1 | |
| SCHEMBL5027949 | 0.85 | TRPA1 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2TRPA1 | |
| SCHEMBL31644897 | 0.85 | TRPA1 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306229-A1 | Transition Metal-Catalyzed Synthesis of Dendritic Polymers | NATIONAL SCIENCE FOUNDATION | 2008-12-11 | — | — | US | disclosed |
| US-20060063859-A1 | Transition metal-catalyzed synthesis of dendritic polymers | NATIONAL SCIENCE FOUNDATION | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063859-A1 | Transition metal-catalyzed synthesis of dendritic polymers | CD14, MICA, PICALM | SMYD2 3315/4885CYP3A4 4174/4885HTT 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.