Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185595 | 0.90 | TSHR (0.51) | TSHRMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL5068488 | 0.86 | TSHR (0.58) | TSHRMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL28075538 | 0.84 | CYP3A4 (0.52) | TSHRMAPK1ALDH1A1CA2LMNA | |
| SCHEMBL12643165 | 0.83 | TAAR1 (0.56) | TSHRMAPK1ALDH1A1VCAM1CA1 | |
| SCHEMBL3334862 | 0.82 | TSHR (0.62) | TSHRMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL21412681 | 0.81 | MAPT (0.50) | TSHRALDH1A1HPGDLMNACYP3A4 | |
| SCHEMBL550266 | 0.80 | TSHR (0.60) | TSHRMAPK1ALDH1A1GAAHPGD | |
| SCHEMBL11967591 | 0.79 | ATM (0.55) | TSHRALDH1A1VCAM1LMNACYP3A4 | |
| SCHEMBL11494839 | 0.79 | MAPT (0.56) | TSHRMAPK1ALDH1A1CA2LMNA | |
| SCHEMBL28823249 | 0.79 | ABCG2 (0.39) | TSHRMAPK1ALDH1A1VCAM1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712680-B2 | Process for reducing aromatic nitro compounds with supported catalyst | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2023-08-01 | — | — | US | disclosed |
| US-20220401927-A1 | PROCESS FOR REDUCING AROMATIC NITRO COMPOUNDS WITH SUPPORTED CATALYST | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-12-22 | — | — | US | disclosed |
| US-11452992-B2 | Iron oxide supported rhodium catalyst for nitroarene reduction | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2022-09-27 | — | — | US | disclosed |
| US-20200298212-A1 | IRON OXIDE SUPPORTED RHODIUM CATALYST FOR NITROARENE REDUCTION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2020-09-24 | — | — | US | disclosed |
| US-7425520-B2 | Catalyst for selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2008-09-16 | — | — | US | disclosed |
| US-20080033193-A1 | CATALYST FOR SELECTIVE HYDROGENATION OF NITRO GROUPS OF HALONITRO AROMATIC COMPOUNDS | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2008-02-07 | — | — | US | disclosed |
| US-7288500-B2 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS TECHNOLOGY INNOVATION, LLC (US) | 2007-10-30 | — | — | US | disclosed |
| US-20070049772-A1 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | HEADWATERS HEAVY OIL, LLC | 2007-03-01 | — | — | US | disclosed |
| EP-0842920-B1 | Process for the production of aromatic halogen-amino compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2004-04-07 | — | — | EP | disclosed |
| US-6197716-B1 | AS HYDROGENATION CATALYST IN HYDROGENATION OF AROMATIC HALONITRO COMPOUNDS TO AROMATIC HALOAMINO COMPOUNDS | NOVARTIS AG (CH) | 2001-03-06 | — | — | US | disclosed |
| US-5962741-A | Process for the production of aromatic halogen-amino compounds | NOVARTIS AG (CH) | 1999-10-05 | — | — | US | disclosed |
| EP-0842920-A2 | Process for the production of aromatic halogen-amino compounds | Novartis AG (CH) | 1998-05-20 | — | — | EP | disclosed |
| US-4020107-A | ACIDIC PHOSPHORUS COMPOUND DEHALOGENATION INHIBITOR | E. I. DU PONT DE NEMOURS AND CO. (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11712680-B2 | Process for reducing aromatic nitro compounds with supported catalyst | ARG2, NDUFS5, NDUFS7 | TSHR 2114/4885MAPK1 2681/4885ALDH1A1 2712/4885 |
| US-20220401927-A1 | PROCESS FOR REDUCING AROMATIC NITRO COMPOUNDS WITH SUPPORTED CATALYST | ARG2, NDUFS5, NDUFS7 | TSHR 2114/4885MAPK1 2681/4885ALDH1A1 2712/4885 |
| US-11452992-B2 | Iron oxide supported rhodium catalyst for nitroarene reduction | ARG2, NOS2, NDUFS7 | TSHR 831/4885MAPK1 3430/4885ALDH1A1 2798/4885 |
| US-20200298212-A1 | IRON OXIDE SUPPORTED RHODIUM CATALYST FOR NITROARENE REDUCTION | ARG2, NOS2, NDUFS7 | TSHR 831/4885MAPK1 3430/4885ALDH1A1 2798/4885 |
| US-20070049772-A1 | Selective hydrogenation of nitro groups of halonitro aromatic compounds | NOXO1, PYM1, HCN4 | TSHR 1264/4885MAPK1 2010/4885ALDH1A1 3031/4885 |
| US-20080033193-A1 | CATALYST FOR SELECTIVE HYDROGENATION OF NITRO GROUPS OF HALONITRO AROMATIC COMPOUNDS | PYM1, NOXO1, SCO2 | TSHR 1294/4885MAPK1 2191/4885ALDH1A1 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.