Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PLK1 | P53350 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15882924 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4EL3MBTL1MAPK1PLK1 | |
| SCHEMBL19675355 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EL3MBTL1MAPK1PLK1 | |
| SCHEMBL31429390 | 0.84 | KDM4E (0.58) | ALDH1A1KDM4EL3MBTL1MAPK1PLK1 | |
| SCHEMBL30373303 | 0.83 | NR4A2 (0.69) | ALDH1A1KDM4EL3MBTL1PLK1MAPT | |
| SCHEMBL2429622 | 0.83 | NR4A2 (0.69) | ALDH1A1KDM4EL3MBTL1PLK1MAPT | |
| SCHEMBL6002325 | 0.82 | CNR2 (0.42) | ALDH1A1KDM4EL3MBTL1MAPK1PLK1 | |
| SCHEMBL2035148 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1MAPK1PLK1 | |
| SCHEMBL5135068 | 0.82 | MEN1 (0.49) | ALDH1A1KDM4EL3MBTL1MAPK1PLK1 | |
| SCHEMBL2035739 | 0.81 | KDM4E (0.56) | ALDH1A1KDM4EL3MBTL1MAPK1PLK1 | |
| SCHEMBL5065671 | 0.81 | CNR2 (0.68) | ALDH1A1PLK1MAPTCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-B1 | Cyanopyrrolidines useful for the treatment of inter alia metabolic syndrome | SANWA KAGAKU KENKYUSHO CO (JP) | 2016-06-08 | — | — | EP | disclosed |
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | DPP4, DPP3, DPP7 | ALDH1A1 2457/4885KDM4E 2352/4885L3MBTL1 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.