Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343062 | 0.89 | ADORA2A (0.67) | ADORA2AADORA2BADORA3ADORA1CYP1A2 | |
| SCHEMBL5794230 | 0.89 | ADORA2A (0.67) | ADORA2AADORA2BADORA3ADORA1CYP1A2 | |
| SCHEMBL7897993 | 0.89 | ADORA2A (0.67) | ADORA2AADORA2BADORA3ADORA1CYP1A2 | |
| SCHEMBL7525475 | 0.88 | ADORA2A (0.66) | ADORA2AADORA2BADORA3ADORA1CYP1A2 | |
| SCHEMBL5621712 | 0.85 | P2RX3 (0.55) | ADORA2AADORA2BADORA3ADORA1CYP1A2 | |
| SCHEMBL2531599 | 0.82 | LMNA (0.63) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL6399918 | 0.80 | ADORA2A (0.76) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL29135435 | 0.80 | ADORA2A (0.76) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL18720690 | 0.79 | LMNA (0.63) | ADORA2AADORA2BADORA3ADORA1CYP1A2 | |
| SCHEMBL2345593 | 0.79 | ADORA2A (0.51) | ADORA2AADORA2BADORA3ADORA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080032945-A1 | 2'-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | US | disclosed |