SCHEMBL5067203

SCHEMBL5067203

Nc1c2nc(c(-c3ccccc3)c3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.71
▸ STAT1 P42224 1/20 0.71
▸ TOP1 P11387 4/20 0.42
▸ CYCS P99999 3/20 0.40
▸ TERT O14746 5/20 0.39
▸ ENPP2 Q13822 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ GFER P55789 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ RCE1 Q9Y256 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11498909 0.99 STAT3 (0.70) STAT3STAT1TOP1CYCSTERT
SCHEMBL5011857 0.96 STAT3 (0.74) STAT3STAT1TOP1CYCSTERT
SCHEMBL29585686 0.92 STAT3 (0.83) STAT3STAT1TOP1CYCSTERT
SCHEMBL226835 0.92 STAT3 (0.83) STAT3STAT1TOP1CYCSTERT
SCHEMBL28009256 0.88 STAT3 (0.65) STAT3STAT1TOP1CYCSTERT
SCHEMBL31550992 0.88 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL30293296 0.88 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL1224432 0.88 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL30753635 0.88 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT
SCHEMBL473158 0.88 STAT3 (0.86) STAT3STAT1TOP1CYCSTERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116273123-B Large-scale preparation method of supported single-atom catalyst 洛阳师范学院 2024-08-20 — — CN claimed
CN-117430771-A Preparation method and application of bimetallic porphyrin-based organic framework material 郑州轻工业大学 2024-01-23 — — CN claimed
CN-116902960-A N and S co-doped carbon material, preparation method and application thereof in zinc-air battery 大连民族大学 2023-10-20 — — CN claimed
CN-116273123-A Large-scale preparation method of supported single-atom catalyst 洛阳师范学院 2023-06-23 — — CN claimed
CN-120718691-A Complex metal fuel catalytic regeneration additive component and preparation method and application thereof 中国石油化工股份有限公司 2025-09-30 — — CN disclosed
CN-116273123-B Large-scale preparation method of supported single-atom catalyst 洛阳师范学院 2024-08-20 — — CN disclosed
CN-117430771-A Preparation method and application of bimetallic porphyrin-based organic framework material 郑州轻工业大学 2024-01-23 — — CN disclosed
CN-117430771-A Preparation method and application of bimetallic porphyrin-based organic framework material 郑州轻工业大学 2024-01-23 — — CN disclosed
CN-117229523-A Ultrathin porphyrin-based benzamide derivative HOFs nano material and preparation method and application thereof 河南大学 2023-12-15 — — CN disclosed
CN-116902960-A N and S co-doped carbon material, preparation method and application thereof in zinc-air battery 大连民族大学 2023-10-20 — — CN disclosed
CN-116273123-A Large-scale preparation method of supported single-atom catalyst 洛阳师范学院 2023-06-23 — — CN disclosed
CN-115725100-A Perovskite quantum dot/4-aminophenylporphyrin/graphene oxide high-thermal-conductivity composite membrane and preparation method thereof 北京科技大学 2023-03-03 — — CN disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 — — US disclosed
EP-1127265-A4 METHOD FOR NON-INVASIVE IMAGING OXYGEN DISTRIBUTION IN MULTI-DIMENSIONS AND APPARATUS THEREFOR OXYGEN ENTPR LTD (US) 2006-01-25 — — EP disclosed
US-6951935-B2 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-10-04 — — US disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-12-25 — — US disclosed
EP-1127265-A1 METHOD FOR NON-INVASIVE IMAGING OXYGEN DISTRIBUTION IN MULTI-DIMENSIONS AND APPARATUS THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2001-08-29 — — EP disclosed
WO-2000026643-A1 METHOD FOR NON-INVASIVE IMAGING OXYGEN DISTRIBUTION IN MULTI-DIMENSIONS AND APPARATUS THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-05-11 — — WO disclosed
US-5539100-A Organic solid state switches incorporating porphyrin compounds and method for producing organic solid state optical switches THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1996-07-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG STAT3 3817/4885STAT1 4312/4885TOP1 1268/4885
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same PPOX, HMBS, UROD STAT3 4156/4885STAT1 3973/4885TOP1 3026/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS STAT3 2986/4885STAT1 3579/4885TOP1 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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