SCHEMBL5067206

SCHEMBL5067206

Nc1c(-c2ccccc2)c2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.52
▸ STAT1 P42224 1/20 0.52
▸ ALDH1A1 P00352 6/20 0.39
▸ SMN1; SMN2 Q16637 5/20 0.39
▸ KDM4E B2RXH2 5/20 0.39
▸ NPC1 O15118 5/20 0.39
▸ RAB9A P51151 5/20 0.39
▸ HPGD P15428 4/20 0.39
▸ TP53 P04637 2/20 0.39
▸ HSD17B10 Q99714 1/20 0.39
▸ PRMT1 Q99873 1/20 0.38
▸ MAPT P10636 4/20 0.37
▸ GAA P10253 3/20 0.37
▸ GFER P55789 2/20 0.37
▸ HTT P42858 2/20 0.37
▸ GLA P06280 1/20 0.37
▸ RCE1 Q9Y256 1/20 0.37
▸ MEN1 O00255 5/20 0.36
▸ KMT2A Q03164 5/20 0.36
▸ XDH P47989 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435710 1.00 STAT3 (0.52) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL31435711 1.00 STAT3 (0.52) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL28218443 0.99 STAT3 (0.51) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL31384904 0.99 STAT3 (0.51) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL28267206 0.99 STAT3 (0.51) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL11498911 0.99 STAT3 (0.51) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL31384898 0.99 STAT3 (0.51) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL31435707 0.99 STAT3 (0.51) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL28088145 0.99 STAT3 (0.51) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL226837 0.89 STAT3 (0.59) STAT3STAT1ALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116273123-B Large-scale preparation method of supported single-atom catalyst 洛阳师范学院 2024-08-20 — — CN claimed
CN-117447663-B Porphyrin-based conjugated organic framework material based on membrane-penetrating peptide modification, and preparation method and application thereof 潍坊医学院 2024-03-08 — — CN claimed
CN-117447663-A Porphyrin-based conjugated organic framework material based on membrane-penetrating peptide modification, and preparation method and application thereof 潍坊医学院 2024-01-26 — — CN claimed
CN-117430771-A Preparation method and application of bimetallic porphyrin-based organic framework material 郑州轻工业大学 2024-01-23 — — CN claimed
CN-116902960-A N and S co-doped carbon material, preparation method and application thereof in zinc-air battery 大连民族大学 2023-10-20 — — CN claimed
CN-116273123-A Large-scale preparation method of supported single-atom catalyst 洛阳师范学院 2023-06-23 — — CN claimed
CN-110137516-B Iron-tin alloy loaded sulfur-nitrogen co-doped carbon electrocatalyst and preparation method thereof 华东师范大学 2022-02-11 — — CN claimed
CN-102417510-A Conjugated Schiff base Zn (zinc) porphyrin as well as preparation and application thereof UNIV NORTHWEST NORMAL 2012-04-18 — — CN claimed
CN-120718691-A Complex metal fuel catalytic regeneration additive component and preparation method and application thereof 中国石油化工股份有限公司 2025-09-30 — — CN disclosed
CN-116273123-B Large-scale preparation method of supported single-atom catalyst 洛阳师范学院 2024-08-20 — — CN disclosed
CN-113754672-B Novel tetrapyrrole compounds and application thereof 上海先辉医药科技有限公司 2024-05-03 — — CN disclosed
CN-115295963-B Polyion liquid modified diaphragm for battery, preparation method and application thereof 华中科技大学 2024-05-03 — — CN disclosed
CN-117447663-B Porphyrin-based conjugated organic framework material based on membrane-penetrating peptide modification, and preparation method and application thereof 潍坊医学院 2024-03-08 — — CN disclosed
CN-117447663-B Porphyrin-based conjugated organic framework material based on membrane-penetrating peptide modification, and preparation method and application thereof 潍坊医学院 2024-03-08 — — CN disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-12-25 — — US disclosed
EP-1127265-A1 METHOD FOR NON-INVASIVE IMAGING OXYGEN DISTRIBUTION IN MULTI-DIMENSIONS AND APPARATUS THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2001-08-29 — — EP disclosed
US-6238931-B1 PARTICLES WITH ENERGY DONORS AND ACCEPTORS AS WELL AS PROTEINS, POLYPEPTIDES, NUCLEIC ACIDS, OR LIGAND ANALOGUES BOUND TO SURFACE; WITH REDUCED QUENCHING AND IMPROVED FLUORESCENCE INTENSITIES; IMMUNOASSAYS BIOSITE DIAGNOSTICS, INC. 2001-05-29 — — US disclosed
WO-2000026643-A1 METHOD FOR NON-INVASIVE IMAGING OXYGEN DISTRIBUTION IN MULTI-DIMENSIONS AND APPARATUS THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-05-11 — — WO disclosed
US-5539100-A Organic solid state switches incorporating porphyrin compounds and method for producing organic solid state optical switches THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1996-07-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same PPOX, HMBS, UROD STAT3 4156/4885STAT1 3973/4885ALDH1A1 3407/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS STAT3 2986/4885STAT1 3579/4885ALDH1A1 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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