SCHEMBL5067336

SCHEMBL5067336

NCCCCc1cn[nH]c1

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AKT2 P31751 1/20 0.56
HRH1 P35367 7/20 0.44
MAOA P21397 1/20 0.43
HRH3 Q9Y5N1 2/20 0.41
HRH4 Q9H3N8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11588923 0.94
Hydrochloric Acid SCHEMBL16862912 0.92 AKT2 (0.61) AKT2HRH1HRH3HRH4
Hydrochloric Acid SCHEMBL31274777 0.92 AKT2 (0.61) AKT2HRH1HRH3HRH4
Hydrochloric Acid SCHEMBL11590343 0.92 AKT2 (0.61) AKT2HRH1HRH3HRH4
SCHEMBL24866428 0.87 AKT2 (0.44) AKT2
SCHEMBL1751652 0.85
Hydrochloric Acid SCHEMBL1549960 0.83 AKT2 (0.46) AKT2HRH3HRH4
Hydrochloric Acid SCHEMBL19437534 0.83
SCHEMBL21263656 0.79 NOS2 (0.44) AKT2
SCHEMBL458851 0.79 TDP1 (0.44) AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025081019-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE IAMBIC THERAPEUTICS, INC. (US) 2025-04-17 WO disclosed
US-20080305041-A1 Pf4 Pharmacophores and Their Uses BIOQUANTA CORP. (US) 2008-12-11 US disclosed
EP-1834267-A2 PF4 PHARMACOPHORES AND THEIR USES Bioquanta Corp. (US) 2007-09-19 EP disclosed
WO-2006055959-A2 PF4 PHARMACOPHORES AND THEIR USES BIOQUANTA CORP. (US) 2006-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080305041-A1 Pf4 Pharmacophores and Their Uses PF4, PXMP4, PFN1 AKT2 4528/4885HRH1 1740/4885MAOA 3952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.