Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5067779

Cc1ccccc1-c1cccc(C(N)=O)c1C.O=C(O)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.47
BCAT2 O15382 1/20 0.44
PDK2 Q15119 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.40
IKBKB O14920 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
TACR1 P25103 1/20 0.39
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HTT P42858 1/20 0.38
PTGER1 P34995 1/20 0.37
PARP1 P09874 1/20 0.37
MEN1 O00255 1/20 0.37
AKR1B10 O60218 1/20 0.37
TRPA1 O75762 1/20 0.37
ABCB11 O95342 1/20 0.37
DHFR P00374 1/20 0.37
MPO P05164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3135445 0.89 MYC (0.53) MYCBCAT2L3MBTL1IKBKBKEAP1
Trifluoroacetic Acid SCHEMBL1785126 0.87 BCAT2 (0.57) MYCBCAT2PDK2L3MBTL1IKBKB
Trifluoroacetic Acid SCHEMBL27999207 0.86 L3MBTL1 (0.44) MYCBCAT2PDK2L3MBTL1LMNA
Trifluoroacetic Acid SCHEMBL1786800 0.82 NPC1 (0.45) MYCBCAT2L3MBTL1LMNAALDH1A1
Trifluoroacetic Acid SCHEMBL5072107 0.82 NPC1 (0.45) MYCBCAT2L3MBTL1LMNAALDH1A1
SCHEMBL30471810 0.80 BCAT2 (0.52) MYCBCAT2KEAP1NFE2L2ALDH1A1
Hydrochloric Acid SCHEMBL18138748 0.79 MYC (0.49) MYCBCAT2L3MBTL1KEAP1NFE2L2
SCHEMBL6173688 0.79 PARP1 (0.53) BCAT2PDK2KEAP1NFE2L2LMNA
Trifluoroacetic Acid SCHEMBL3979895 0.79 MYC (0.39) MYCBCAT2PDK2L3MBTL1IKBKB
SCHEMBL5720757 0.77 MYC (0.65) MYCL3MBTL1LMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1954682-A1 NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER S DISEASE, NEURODEGENERATION AND DEMENTIA Astra Zeneca AB (SE) 2008-08-13 EP claimed
WO-2007058601-A1 NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER’S DISEASE, NEURODEGENERATION AND DEMENTIA ASTRAZENECA AB (SE) 2007-05-24 WO claimed