Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.57 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034930 | 0.91 | BCAT2 (0.69) | BCAT2PDCD1CD274HNF4AMYC | |
| SCHEMBL530285 | 0.91 | BCAT2 (0.69) | BCAT2PDCD1CD274HNF4AMYC | |
| Trifluoroacetic Acid SCHEMBL5067779 | 0.87 | MYC (0.47) | BCAT2PDK2MYCMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1786045 | 0.85 | BCAT2 (0.79) | BCAT2PDK2HNF4AMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL31255509 | 0.85 | BCAT2 (0.79) | BCAT2PDK2HNF4AMEN1KMT2A | |
| SCHEMBL6307908 | 0.84 | BCAT2 (0.65) | BCAT2PDCD1CD274HNF4AMYC | |
| SCHEMBL1885577 | 0.82 | PARP1 (0.50) | BCAT2PDK2SMN1; SMN2PARP1 | |
| Trifluoroacetic Acid SCHEMBL27999207 | 0.81 | L3MBTL1 (0.44) | BCAT2PDK2MYCMEN1KMT2A | |
| SCHEMBL17803632 | 0.80 | SLC6A4 (0.51) | BCAT2MEN1KMT2AKEAP1NFE2L2 | |
| Trifluoroacetic Acid SCHEMBL18049957 | 0.79 | BCAT2 (0.52) | BCAT2PDK2PDCD1CD274HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124559-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | SMITHKLINE BEECHAM CORPORATION (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124559-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | OPRL1, OPRM1, OPRK1 | BCAT2 2529/4885PDK2 4021/4885PDCD1 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.