SCHEMBL5068252

SCHEMBL5068252

O=C(CS)OCC(S)CS.O=C(CS)OCC(S)CS

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.39
TSHR P16473 1/20 0.39
NR1I2 O75469 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330897 1.00 HSD17B10 (0.39) HSD17B10TSHRNR1I2ALDH1A1LMNA
SCHEMBL21835883 0.86 LMNA (0.36) HSD17B10TSHRNR1I2ALDH1A1LMNA
SCHEMBL22721833 0.82 ALDH1A1 (0.42) HSD17B10TSHRNR1I2ALDH1A1LMNA
SCHEMBL331859 0.82 LMNA (0.33) HSD17B10TSHRNR1I2ALDH1A1LMNA
SCHEMBL23152032 0.80 NR1I2 (0.32) HSD17B10NR1I2ALDH1A1LMNACYP1A2
SCHEMBL28895315 0.80 SLC22A6 (0.35) HSD17B10NR1I2ALDH1A1LMNACYP1A2
SCHEMBL20474965 0.79 PRKCA (0.36) HSD17B10NR1I2ALDH1A1LMNACYP1A2
SCHEMBL2172101 0.79 LMNA (0.38) ALDH1A1LMNA
SCHEMBL1593724 0.77 TSHR (0.43) HSD17B10TSHRTDP1
SCHEMBL332035 0.77 LMNA (0.33) HSD17B10NR1I2ALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116438214-A Sealing material for organic EL display element, cured product thereof, and organic EL display device 三井化学株式会社 2023-07-14 CN disclosed
CN-108350135-B Curable composition, adhesive, article having coating layer, fiber-reinforced composite material, and curable composition set 三菱化学株式会社 2021-11-23 CN disclosed
CN-109563269-B Aromatic polythiol compound for optical material SKC株式会社 2021-07-23 CN disclosed
CN-108350147-B Curable composition, adhesive, article having coating layer, fiber-reinforced composite material, potting agent, and curable composition kit 三菱化学株式会社 2021-07-06 CN disclosed
EP-1505094-B1 THIOURETHANE-BASED OPTICAL MATERIAL MITSUI CHEMICALS INC (JP) 2014-01-22 EP disclosed
US-7396900-B2 Thiourethane-based optical material MITSUI CHEMICALS, INC. (JP) 2008-07-08 US disclosed
US-7244808-B2 Thiourethane-based optical material MITSUI CHEMICALS, INC. (JP) 2007-07-17 US disclosed
US-20050131203-A1 Thiourethane-based optical material MITSUI CHEMICALS, INC. (JP) 2005-06-16 US disclosed
EP-1138670-B1 Polythiol, polymerizable composition, resin and lens, and process for preparing thiol compound MITSUI CHEMICALS INC (JP) 2005-05-25 EP disclosed
EP-1505094-A1 THIOURETHANE-BASED OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2005-02-09 EP disclosed
US-5693738-A REACTING AN ISOCYANATE AND/OR AN ISOTHIOCYANATE COMPOUND WITH A HYDROXYL AND/OR MERCAPTO-CONTAINING COMPOUND IN THE PRESENCE OF A COMPLEX OF A TERTIARY AMINE AND A LEWIS ACID MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-02 US disclosed
US-5652321-A Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-29 US disclosed
EP-0506315-B1 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS (JP) 1996-08-14 EP disclosed
EP-0713105-A2 Composition for optical materials and use thereof MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-05-22 EP disclosed
EP-0676429-A2 Composition for urethane-base plastic lens MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-11 EP disclosed
EP-0422836-B1 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS (JP) 1994-08-24 EP disclosed
US-5194559-A Reacting compounds containing isocyanate and isothiocyanate groups with polyol and polythiol; colorlrss, transparent MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-16 US disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
US-5059673-A bis(isocyanatomethyl)-norbornane or -4,7methonohexahydroindan e high refractive index, lightweight, high impact MITSUI TOATSU CHEMICALS, INC. (JP) 1991-10-22 US disclosed
EP-0422836-A2 Resin for urethane lenses, lenses comprising the resin, and a process for preparation of the resin and the lenses MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-04-17 EP disclosed