SCHEMBL9475478

SCHEMBL9475478

O=S(=O)(c1ccc(Cl)cc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
CYP3A4 P08684 1/20 0.60
MAPK1 P28482 1/20 0.60
TSHR P16473 2/20 0.53
ALOX15 P16050 2/20 0.53
POLB P06746 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
MCL1 Q07820 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
AKR1B1 P15121 1/20 0.50
CNR2 P34972 1/20 0.49
HPGD P15428 2/20 0.49
KIF18A Q8NI77 1/20 0.47
HSD11B1 P28845 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.46
USP2 O75604 1/20 0.46
PPARG P37231 1/20 0.46
KDM4E B2RXH2 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13321682 0.89 ALDH1A1 (0.48) ALDH1A1CYP3A4MAPK1TSHRALOX15
SCHEMBL13309929 0.89 KIF18A (0.58) ALDH1A1CYP3A4MAPK1TSHRALOX15
SCHEMBL13321641 0.89 ALDH1A1 (0.53) ALDH1A1CYP3A4MAPK1TSHRALOX15
SCHEMBL1533667 0.89 PTGDR2 (0.49) ALDH1A1CYP3A4MAPK1TSHRALOX15
SCHEMBL12696990 0.89 POLB (0.54) ALDH1A1CYP3A4MAPK1TSHRALOX15
SCHEMBL10656611 0.89 MEN1 (0.63) ALDH1A1CYP3A4MAPK1TSHRALOX15
SCHEMBL228959 0.88 KIF18A (0.57) ALDH1A1CYP3A4MAPK1TSHRALOX15
SCHEMBL5068459 0.87 MCL1 (0.57) ALDH1A1MAPK1TSHRALOX15L3MBTL1
Tetradifon SCHEMBL8341082 0.83 ALDH1A1 (0.60) ALDH1A1CYP3A4MAPK1ALOX15POLB
SCHEMBL5481274 0.83 HSD11B1 (0.62) ALDH1A1CYP3A4MAPK1ALOX15POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US claimed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
US-5179193-A From dihaloaromatic sulfone, polyhalodiarylsulfone and polymerizable sulfur source; coatings, films, moldings, fibers PHILLIPS PETROLEUM COMPANY (US) 1993-01-12 US disclosed