Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 7/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510787 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL25297559 | 0.79 | P2RX7 (0.47) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL15909256 | 0.79 | P2RX7 (0.47) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL25297558 | 0.79 | P2RX7 (0.47) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL27833236 | 0.78 | ALDH1A1 (0.38) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL22341347 | 0.78 | ALDH1A1 (0.38) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL27076419 | 0.78 | ALDH1A1 (0.38) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL20774033 | 0.78 | DPP4 (0.51) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL11211642 | 0.78 | EPHX1 (0.46) | ALDH1A1EPHX1CA12CA1CA2 | |
| SCHEMBL20773524 | 0.76 | CYP2D6 (0.40) | ALDH1A1EPHX1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318947-A1 | Inhibitors of Akt Activity | HEERDING DIRK A | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318947-A1 | Inhibitors of Akt Activity | PI4KB, PIK3CA, AKT2 | ALDH1A1 4166/4885EPHX1 4184/4885CA12 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.