SCHEMBL9494472

SCHEMBL9494472

O=C(O)CC(=O)N1CCSC1

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 16/20 0.45
DPP7 Q9UHL4 10/20 0.43
DPP8 Q6V1X1 4/20 0.41
DPP9 Q86TI2 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9031999 0.87 FAAH (0.41) DPP7
SCHEMBL10722676 0.82 DPP4 (0.44) DPP4DPP7DPP8DPP9
SCHEMBL10611575 0.80 DPP4 (0.47) DPP4DPP7DPP8DPP9
SCHEMBL10611650 0.80 DPP4 (0.44) DPP4DPP7DPP8DPP9
SCHEMBL4419351 0.79 DPP4 (0.48) DPP4DPP7DPP8DPP9
SCHEMBL4160072 0.77
SCHEMBL6052795 0.77
SCHEMBL5069160 0.77
SCHEMBL8264016 0.77
Hydrochloric Acid SCHEMBL6162602 0.75 DPP7 (0.51) DPP4DPP7DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0333080-B1 BETA-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1993-10-13 EP disclosed
US-5206254-A Antitussive agents BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1993-04-27 US disclosed
EP-0269352-B1 ASSAY FOR SULFHYDRYL AMINO ACIDS AND METHODS FOR DETECTING AND DISTINGUISHING COBALAMIN AND FOLIC ACID DEFICIENCY UNIVERSITY PATENTS, INC. (US) 1993-03-17 EP disclosed
EP-0486118-A1 Method for detecting cobalamin and folic acid deficiency COMPETITIVE TECHNOLOGIES INC. (US) 1992-05-20 EP disclosed
EP-0407403-A1 BETA-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) 1991-01-16 EP disclosed
WO-1989008648-A1 beta-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-09-21 WO disclosed
EP-0333080-A1 Beta-carbonyl-carboxyamides of 1,3-thiazolidines BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-09-20 EP disclosed
EP-0269352-A2 Assay for sulfhydryl amino acids and methods for detecting and distinguishing cobalamin and folic acid deficiency UNIVERSITY PATENTS, INC. (US) 1988-06-01 EP disclosed