Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794825 | 1.00 | CTSV (0.43) | CTSVCTSLSRD5A1SRD5A2CFD | |
| SCHEMBL5069977 | 0.90 | RAPGEF4 (0.41) | LMNAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5796339 | 0.87 | CTSV (0.41) | CTSVCTSLSRD5A1SRD5A2CFD | |
| SCHEMBL5795248 | 0.83 | SRD5A1 (0.41) | CTSVCTSLSRD5A1SRD5A2CFD | |
| SCHEMBL1780128 | 0.82 | CCNE1 (0.41) | CTSVCTSLSRD5A1SRD5A2OPRM1 | |
| SCHEMBL1748701 | 0.82 | CCNE1 (0.41) | CTSVCTSLSRD5A1SRD5A2OPRM1 | |
| SCHEMBL1748944 | 0.81 | CTSV (0.40) | CTSVCTSLSRD5A1SRD5A2OPRM1 | |
| SCHEMBL5797369 | 0.78 | MAPT (0.42) | LMNAMAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5795867 | 0.75 | MAPT (0.39) | LMNAMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5795964 | 0.74 | HTR6 (0.42) | MAPTALDH1A1SMN1; SMN2RAPGEF4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1990343-A2 | Azaindoles | Aventis Pharma Limited (GB) | 2008-11-12 | — | — | EP | disclosed |